Insulin rather than glucose homoeostasis in the pathophysiology of diabetes.
Hepatic glucose efflux is very sensitive to changes in plasma-insulin and it is postulated that this provides an important feedback control of insulin secretion. In diabetes this hepatic "insulin sensor" increases the basal plasma-glucose until the impaired beta cells are sufficiently stim...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1976
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