Co-receptor and co-stimulation blockade for mixed chimerism and tolerance without myelosuppressive conditioning
<p style="text-align:justify;"> <b>Background:</b> A major challenge in the application of marrow transplantation as a route to immunological tolerance of a transplanted organ is to achieve hematopoietic stem cell (HSC) engraftment with minimal myelosuppressive treatment...
Main Authors: | Graca, L, Daley, S, Fairchild, P, Cobbold, S, Waldmann, H |
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Format: | Journal article |
Language: | English |
Published: |
BioMed Central
2006
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