Evaluation of CRISPR-Cas9 approaches to investigate microRNA targeting in human chondrocytes
<p>Micro RNAs (miRNAs) are small, non-coding, negative regulators of genes that play a major role in a wide variety of biological and pathological processes. The chondrocyte-selective miR-140 is required for normal cartilage development, as demonstrated by the developmental defects in miR-140...
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| Format: | Thesis |
| Language: | English |
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2019
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