Identification of compounds that bind the centriolar protein SAS-6 and inhibit its oligomerisation

Identification of compounds that bind the centriolar protein SAS-6 and inhibit its oligomerisation

Centrioles are key eukaryotic organelles that are responsible for the formation of cilia and flagella, and for organizing the microtubule network and the mitotic spindle in animals. Centriole assembly requires oligomerization of the essential protein spindle assembly abnormal 6 (SAS-6), which forms...

書目詳細資料
Main Authors:	Busch, J, Matsoukas, M-T, Musgaard, M, Spyroulias, G, Biggin, P, Vakonakis, I
格式:	Journal article
語言:	English
出版:	American Society for Biochemistry and Molecular Biology 2020

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