Polygenic risk scores for pan-cancer risk prediction in the Chinese population: A population-based cohort study based on the China Kadoorie Biobank

Polygenic risk scores for pan-cancer risk prediction in the Chinese population: A population-based cohort study based on the China Kadoorie Biobank

Background: Polygenic risk scores (PRSs) have been extensively developed for cancer risk prediction in European populations, but their effectiveness in the Chinese population remains uncertain. Methods and findings: We constructed 80 PRSs for the 13 most common cancers using seven schemes and evalua...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Zhu, M, Zhu, X, Han, Y, Ma, Z, Ji, C, Wang, T, Yan, C, Song, C, Yu, C, Sun, D, Jiang, Y, Chen, J, Yang, L, Chen, Y, Du, H, Walters, R, Millwood, IY, Dai, J, Ma, H, Zhang, Z, Chen, Z, Hu, Z, Lv, J, Jin, G
Формат:	Journal article
Хэл сонгох:	English
Хэвлэсэн:	Public Library of Science 2025

Ижил төстэй зүйлс

Minimal improvement in coronary artery disease risk prediction in Chinese population using polygenic risk scores: evidence from the China Kadoorie Biobank
-н: Yang, S, зэрэг
Хэвлэсэн: (2023)

Polygenic risk scores for pan-cancer risk prediction in the Chinese population: A population-based cohort study based on the China Kadoorie Biobank.
-н: Meng Zhu, зэрэг
Хэвлэсэн: (2025-02-01)

Genotyping and population characteristics of the China Kadoorie Biobank
-н: Walters, R, зэрэг
Хэвлэсэн: (2023)

Spicy food consumption and risk of gastrointestinal-tract cancers: findings from the China Kadoorie Biobank
-н: Chan, W, зэрэг
Хэвлэсэн: (2021)

Problem drinking, wellbeing and mortality risk in Chinese men: findings from the China Kadoorie Biobank
-н: Im, P, зэрэг
Хэвлэсэн: (2019)

External validation of models for predicting risk of colorectal cancer using the China Kadoorie Biobank
-н: Abhari, R, зэрэг
Хэвлэсэн: (2022)

A genome-wide association study based on the China Kadoorie Biobank identifies genetic associations between snoring and cardiometabolic traits
-н: Zhu, Y, зэрэг
Хэвлэсэн: (2024)

Minimal improvement in coronary artery disease risk prediction in Chinese population using polygenic risk scores: evidence from the China Kadoorie Biobank
-н: Songchun Yang, зэрэг
Хэвлэсэн: (2023-10-01)

A high-resolution haplotype-resolved reference panel constructed from the China Kadoorie Biobank Study
-н: Yu, C, зэрэг
Хэвлэсэн: (2023)

Modification effect of ideal cardiovascular health metrics on genetic association with incident heart failure in the China Kadoorie Biobank and the UK Biobank
-н: Yang, R, зэрэг
Хэвлэсэн: (2021)

Dietary patterns and insomnia symptoms in Chinese adults: the China Kadoorie Biobank
-н: Yu, C, зэрэг
Хэвлэсэн: (2017)

Risk prediction for cardiovascular disease using ECG data in the China Kadoorie Biobank
-н: Shen, Y, зэрэг
Хэвлэсэн: (2016)

Depression, anxiety, and prevalent diabetes in the Chinese population: findings from the China Kadoorie Biobank of 0.5 million people.
-н: Mezuk, B, зэрэг
Хэвлэсэн: (2013)

Depression, anxiety, and prevalent diabetes in the Chinese population: Findings from the China Kadoorie Biobank of 0.5million people
-н: Mezuk, B, зэрэг
Хэвлэсэн: (2013)

Parenthood and the risk of cardiovascular diseases among 0.5 million men and women: findings from the China Kadoorie Biobank
-н: Peters, S, зэрэг
Хэвлэсэн: (2016)

Associations of blood glucose and prevalent diabetes with risk of cardiovascular disease in 500 000 adult Chinese: the China Kadoorie Biobank.
-н: Bragg, F, зэрэг
Хэвлэсэн: (2014)

Parenthood and the risk of cardiovascular diseases among 0.5 million men and women: findings from the China Kadoorie Biobank
-н: Peters, S, зэрэг
Хэвлэсэн: (2016)

Association of heart rate and diabetes among 0.5 million adults in the China Kadoorie biobank: Results from observational and Mendelian randomization analyses
-н: Wang, W, зэрэг
Хэвлэсэн: (2021)

Red meat, poultry and fish consumption and risk of diabetes: a 9 year prospective cohort study of the China Kadoorie Biobank
-н: Du, H, зэрэг
Хэвлэсэн: (2020)

Self-rated health status and risk of ischemic heart disease in the China Kadoorie Biobank study: a population based cohort study
-н: Dong, W, зэрэг
Хэвлэсэн: (2017)

Genome-wide polygenic risk score, cardiometabolic risk factors, and type 2 diabetes mellitus in the Chinese population
-н: Huang, N, зэрэг
Хэвлэсэн: (2023)

Patterns and trends of alcohol consumption in rural and urban areas of China: findings from the China Kadoorie Biobank
-н: Im, PK, зэрэг
Хэвлэсэн: (2019)

The relative validity and reproducibility of food frequency questionnaires in the China Kadoorie Biobank Study
-н: Qin, C, зэрэг
Хэвлэсэн: (2022)

Polygenic risk scores for prediction of breast cancer risk in Asian populations
-н: Ho, W-K, зэрэг
Хэвлэсэн: (2021)

Associations of polygenic risk scores with risks of stroke and its subtypes in Chinese
-н: Yang, S, зэрэг
Хэвлэсэн: (2023)

Pregnancy, pregnancy loss and the risk of cardiovascular disease in Chinese women: findings from the China Kadoorie Biobank
-н: Peters, S, зэрэг
Хэвлэсэн: (2017)

The association of physical activity with plasma lipoproteins and inflammation measured by NMR-metabolomics: evidence from the China Kadoorie Biobank study
-н: Pang, Y, зэрэг
Хэвлэсэн: (2017)

Association of exhaled carbon monoxide with risk of cardio-cerebral-vascular disease in the China Kadoorie Biobank cohort study
-н: Qiu, G, зэрэг
Хэвлэсэн: (2020)

Fresh fruit consumption and all-cause and cause-specific mortality: findings from the China Kadoorie Biobank
-н: Du, H, зэрэг
Хэвлэсэн: (2017)

Dairy consumption and risk of cancer: an 11 year prospective cohort study of the China Kadoorie Biobank
-н: Kakkoura, M, зэрэг
Хэвлэсэн: (2021)

Self-rated health status and risk of incident stroke in 0.5 million Chinese adults: The China Kadoorie Biobank Study
-н: Dong, W, зэрэг
Хэвлэсэн: (2018)

Evaluation of type 2 diabetes genetic risk variants in Chinese adults: findings from 93,000 individuals from the China Kadoorie Biobank
-н: Gan, W, зэрэг
Хэвлэсэн: (2016)

Association of major depression with risk of ischemic heart disease in a mega-cohort of Chinese adults: the China Kadoorie Biobank Study
-н: Liu, N, зэрэг
Хэвлэсэн: (2016)

The distribution and correlates of self-rated health in elderly Chinese: the China Kadoorie Biobank study
-н: Song, X, зэрэг
Хэвлэсэн: (2019)

Lactation duration and the risk of subtypes of stroke among parous postmenopausal women from the China Kadoorie Biobank
-н: Ren, Z, зэрэг
Хэвлэсэн: (2022)

[Regional differences in patterns of alcohol consumption: findings from the China Kadoorie Biobank study on half a million people from 10 regions].
-н: Lyu, J, зэрэг
Хэвлэсэн: (2014)

Device-measured movement behaviours in over 20,000 China Kadoorie Biobank participants
-н: Chen, Y, зэрэг
Хэвлэсэн: (2023)

Development of a model to predict 10-year risk of ischemic and hemorrhagic stroke and ischemic heart disease using the China Kadoorie Biobank
-н: Yang, S, зэрэг
Хэвлэсэн: (2022)

Early adulthood BMI and cardiovascular disease: a prospective cohort study from the China Kadoorie Biobank
-н: Chen, Y, зэрэг
Хэвлэсэн: (2024)

Menopause and risk of hip fracture in middle-aged Chinese women a 10-year follow-up of China Kadoorie Biobank
-н: Peng, KP, зэрэг
Хэвлэсэн: (2019)