Polygenic risk scores for pan-cancer risk prediction in the Chinese population: A population-based cohort study based on the China Kadoorie Biobank

Polygenic risk scores for pan-cancer risk prediction in the Chinese population: A population-based cohort study based on the China Kadoorie Biobank

Background: Polygenic risk scores (PRSs) have been extensively developed for cancer risk prediction in European populations, but their effectiveness in the Chinese population remains uncertain. Methods and findings: We constructed 80 PRSs for the 13 most common cancers using seven schemes and evalua...

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Huvudupphovsmän: Zhu, M, Zhu, X, Han, Y, Ma, Z, Ji, C, Wang, T, Yan, C, Song, C, Yu, C, Sun, D, Jiang, Y, Chen, J, Yang, L, Chen, Y, Du, H, Walters, R, Millwood, IY, Dai, J, Ma, H, Zhang, Z, Chen, Z, Hu, Z, Lv, J, Jin, G
Materialtyp: Journal article
Språk:English
Publicerad: Public Library of Science 2025

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