Inhibition of human ovarian carcinoma cell- and hexosaminidase- mediated degradation of extracellular matrix by sugar analogs.

Inhibition of human ovarian carcinoma cell- and hexosaminidase- mediated degradation of extracellular matrix by sugar analogs.

Human ovarian carcinoma (HOC) cell beta-N-acetylglucosaminidase (beta-NAG, EC 3.2.1.30) was found to be present in three isoenzymatic forms. All three forms were capable of degrading ECM. Therefore, inhibitors of beta-NAG were sought as potential anti-invasive agents. Two sugar analogs, 2-acetamido-...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Woynarowska, B, Wikiel, H, Sharma, M, Carpenter, N, Fleet, G, Bernacki, R
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	1992

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