Up-regulation of utrophin alleviates the dystrophic phenotype in the mdx mouse heart

Eitemau Tebyg

• Non-toxic ubiquitous overexpression of utrophin in the mdx mouse.
  gan: Fisher, R, et al.
  Cyhoeddwyd: (2000)
• Non-toxic ubiquitous over-expression of utrophin in the mdx mouse.
  gan: Fisher, R, et al.
  Cyhoeddwyd: (2001)
• Prevention of the dystrophic phenotype in dystrophin/utrophin-deficient muscle following adenovirus-mediated transfer of a utrophin minigene.
  gan: Wakefield, P, et al.
  Cyhoeddwyd: (2000)
• Daily treatment with SMTC1100, a novel small molecule utrophin upregulator, dramatically reduces the dystrophic symptoms in the mdx mouse.
  gan: Tinsley, J, et al.
  Cyhoeddwyd: (2011)
• A-utrophin up-regulation in mdx skeletal muscle is independent of regeneration.
  gan: Weir, A, et al.
  Cyhoeddwyd: (2004)