Annexin-A1: Therapeutic potential in microvascular disease

Annexin-A1: Therapeutic potential in microvascular disease

Annexin-A1 (ANXA1) was first discovered in the early 1980's as a protein, which mediates (some of the) anti-inflammatory effects of glucocorticoids. Subsequently, the role of ANXA1 in inflammation has been extensively studied. The biology of ANXA1 is complex and it has many different roles in b...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Purvis, G, Solito, E, Thiemermann, C
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	Frontiers Media 2019

Eitemau Tebyg

Annexin A1 attenuates microvascular complications through restoration of Akt signalling in a murine model of type 1 diabetes
gan: Purvis, G, et al.
Cyhoeddwyd: (2017)

Therapeutic potential for targeting Annexin A1 in fibrotic diseases
gan: Zhibin Yan, et al.
Cyhoeddwyd: (2022-11-01)

Annexin 1 and the regulation of endocrine function.
gan: John, C, et al.
Cyhoeddwyd: (2004)

Annexin A1 in the brain--undiscovered roles?
gan: Solito, E, et al.
Cyhoeddwyd: (2008)

Annexin 1, glucocorticoids, and the neuroendocrine-immune interface.
gan: Buckingham, J, et al.
Cyhoeddwyd: (2006)

Annexin A1 alleviates microvascular complications in type 1 diabetic mice
gan: BIAN Fang, LI Ning, LI Qi, LI Kang, JIN Wen
Cyhoeddwyd: (2021-04-01)

Expression of annexins 1 and 5 in human pituitary tumours
gan: Mulla, A, et al.
Cyhoeddwyd: (2000)

Annexin A1, an essential component for blood brain barrier tightness: pathological and therapeutic implications
gan: Cristante, E, et al.
Cyhoeddwyd: (2015)

Annexin 1: a mediator of glucocorticoid action at the neuroendocrine-immune interface.
gan: Buckingham, J, et al.
Cyhoeddwyd: (2006)

Annexin 1: a mediator of glucocorticoid action at the neuroendocrine-immune interface.
gan: Buckingham, J, et al.
Cyhoeddwyd: (2006)

The cellular exportation of annexin 1 requires post-translational modification
gan: Buckingham, J, et al.
Cyhoeddwyd: (2006)

Therapeutic Potential of Annexins in Sepsis and COVID-19
gan: Louise Mui, et al.
Cyhoeddwyd: (2021-09-01)

Therapeutic Potential of Annexin A1 Modulation in Kidney and Cardiovascular Disorders
gan: Mahmood S. Mozaffari
Cyhoeddwyd: (2021-12-01)

Annexin A1: a central player in the anti-inflammatory and neuroprotective role of microglia.
gan: McArthur, S, et al.
Cyhoeddwyd: (2010)

Identification of AnnexinA1 as an Endogenous Regulator of RhoA, and Its Role in the Pathophysiology and Experimental Therapy of Type-2 Diabetes
gan: Gareth S. D. Purvis, et al.
Cyhoeddwyd: (2019-03-01)

Annexin 1: a paracrine/juxtacrine mediator of glucorticoid action in the neuroendocrine system.
gan: Buckingham, J, et al.
Cyhoeddwyd: (2003)

Kinase-dependent regulation of the secretion of thyrotrophin and luteinizing hormone by glucocorticoids and annexin 1 peptides.
gan: John, C, et al.
Cyhoeddwyd: (2003)

Estrogen Promotes Pro-resolving Microglial Behavior and Phagocytic Cell Clearance Through the Actions of Annexin A1
gan: Rodrigo Azevedo Loiola, et al.
Cyhoeddwyd: (2019-06-01)

Annexin A1 regulates hormone exocytosis through a mechanism involving actin reorganization.
gan: McArthur, S, et al.
Cyhoeddwyd: (2009)

Annexin 1 dependent actions of glucocorticoids in the anterior pituitary gland - role of the formyl peptide receptor family
gan: Buckingham, J, et al.
Cyhoeddwyd: (2006)

Post-translational modification plays an essential role in the translocation of annexin A1 from the cytoplasm to the cell surface.
gan: Solito, E, et al.
Cyhoeddwyd: (2006)

Post-translational modification plays an essential role in the translocation of annexin A1 from the cytoplasm to the cell surface
gan: Solito, E, et al.
Cyhoeddwyd: (2006)

Formyl peptide receptors and the regulation of ACTH secretion: targets for annexin A1, lipoxins, and bacterial peptides.
gan: John, C, et al.
Cyhoeddwyd: (2007)

Gene deletion reveals roles for annexin A1 in the regulation of lipolysis and IL-6 release in epididymal adipose tissue.
gan: Warne, J, et al.
Cyhoeddwyd: (2006)

Annexin 1-dependent actions of glucocorticoids in the anterior pituitary gland: roles of the N-terminal domain and protein kinase C.
gan: John, C, et al.
Cyhoeddwyd: (2002)

Expression, subcellular localization and phosphorylation status of annexins 1 and 5 in human pituitary adenomas and a growth hormone-secreting carcinoma.
gan: Mulla, A, et al.
Cyhoeddwyd: (2004)

AnnexinA6: a potential therapeutic target gene for extracellular matrix mineralization
gan: Jie Yang, et al.
Cyhoeddwyd: (2023-09-01)

Induction of annexin-1 at transcriptional and post-transcriptional level in rat brain by methylprednisolone and the 21-aminosteroid U74389F
gan: P. H. Voermans, et al.
Cyhoeddwyd: (1996-01-01)

Annexin A2 and Kidney Diseases
gan: Ling Lin, et al.
Cyhoeddwyd: (2022-09-01)

Evidence from studies on co-cultures of TtT/GF and AtT20 cells that Annexin 1 acts as a paracrine or juxtacrine mediator of the early inhibitory effects of glucocorticoids on ACTH release.
gan: Tierney, T, et al.
Cyhoeddwyd: (2003)

Expression and externalization of annexin 1 in the adrenal gland: structure and function of the adrenal gland in annexin 1-null mutant mice.
gan: Davies, E, et al.
Cyhoeddwyd: (2007)

Expression and externalization of annexin 1 in the adrenal gland: structure and function of the adrenal gland in annexin 1-null mutant mice
gan: Davies, E, et al.
Cyhoeddwyd: (2007)

Annexin 1: a local paracrine regulator of adrenal size and corticosterone secretion: evidence from annexin 1-null mice
gan: Morris, J, et al.
Cyhoeddwyd: (2007)

Annexin in plants
gan: Phang, Ing Chia
Cyhoeddwyd: (2006)

Inhibitory role of Annexin A1 in pathological bone resorption and therapeutic implications in periprosthetic osteolysis
gan: Hend Alhasan, et al.
Cyhoeddwyd: (2022-07-01)

Annexin A1 in the nervous and ocular systems
gan: Aijia Wang, et al.
Cyhoeddwyd: (2024-01-01)

Contribution of annexin A1 to anticancer immunosurveillance
gan: Elisa Elena Baracco, et al.
Cyhoeddwyd: (2019-11-01)

Participation of annexin 1 in the response of Arabidopsis thaliana to lead exposure: potential for phytoremediation
gan: Phang, Ing Chia, et al.
Cyhoeddwyd: (2009)

Annexin A2-mediated cancer progression and therapeutic resistance in nasopharyngeal carcinoma
gan: Chang-Yu Chen, et al.
Cyhoeddwyd: (2018-03-01)

HDX-MS for Epitope Characterization of a Therapeutic ANTIBODY Candidate on the Calcium-Binding Protein Annexin-A1
gan: Marius Gramlich, et al.
Cyhoeddwyd: (2021-03-01)