Annexin-A1: Therapeutic potential in microvascular disease

Annexin-A1: Therapeutic potential in microvascular disease

Annexin-A1 (ANXA1) was first discovered in the early 1980's as a protein, which mediates (some of the) anti-inflammatory effects of glucocorticoids. Subsequently, the role of ANXA1 in inflammation has been extensively studied. The biology of ANXA1 is complex and it has many different roles in b...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí:	Purvis, G, Solito, E, Thiemermann, C
Formáid:	Journal article
Teanga:	English
Foilsithe / Cruthaithe:	Frontiers Media 2019

Míreanna comhchosúla

Annexin A1 attenuates microvascular complications through restoration of Akt signalling in a murine model of type 1 diabetes
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Foilsithe / Cruthaithe: (2017)

Therapeutic potential for targeting Annexin A1 in fibrotic diseases
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Foilsithe / Cruthaithe: (2022-11-01)

Annexin 1 and the regulation of endocrine function.
de réir: John, C, et al.
Foilsithe / Cruthaithe: (2004)

Annexin A1 in the brain--undiscovered roles?
de réir: Solito, E, et al.
Foilsithe / Cruthaithe: (2008)

Annexin 1, glucocorticoids, and the neuroendocrine-immune interface.
de réir: Buckingham, J, et al.
Foilsithe / Cruthaithe: (2006)

Annexin A1 alleviates microvascular complications in type 1 diabetic mice
de réir: BIAN Fang, LI Ning, LI Qi, LI Kang, JIN Wen
Foilsithe / Cruthaithe: (2021-04-01)

Expression of annexins 1 and 5 in human pituitary tumours
de réir: Mulla, A, et al.
Foilsithe / Cruthaithe: (2000)

Annexin A1, an essential component for blood brain barrier tightness: pathological and therapeutic implications
de réir: Cristante, E, et al.
Foilsithe / Cruthaithe: (2015)

Annexin 1: a mediator of glucocorticoid action at the neuroendocrine-immune interface.
de réir: Buckingham, J, et al.
Foilsithe / Cruthaithe: (2006)

Annexin 1: a mediator of glucocorticoid action at the neuroendocrine-immune interface.
de réir: Buckingham, J, et al.
Foilsithe / Cruthaithe: (2006)

The cellular exportation of annexin 1 requires post-translational modification
de réir: Buckingham, J, et al.
Foilsithe / Cruthaithe: (2006)

Therapeutic Potential of Annexins in Sepsis and COVID-19
de réir: Louise Mui, et al.
Foilsithe / Cruthaithe: (2021-09-01)

Therapeutic Potential of Annexin A1 Modulation in Kidney and Cardiovascular Disorders
de réir: Mahmood S. Mozaffari
Foilsithe / Cruthaithe: (2021-12-01)

Annexin A1: a central player in the anti-inflammatory and neuroprotective role of microglia.
de réir: McArthur, S, et al.
Foilsithe / Cruthaithe: (2010)

Identification of AnnexinA1 as an Endogenous Regulator of RhoA, and Its Role in the Pathophysiology and Experimental Therapy of Type-2 Diabetes
de réir: Gareth S. D. Purvis, et al.
Foilsithe / Cruthaithe: (2019-03-01)

Annexin 1: a paracrine/juxtacrine mediator of glucorticoid action in the neuroendocrine system.
de réir: Buckingham, J, et al.
Foilsithe / Cruthaithe: (2003)

Kinase-dependent regulation of the secretion of thyrotrophin and luteinizing hormone by glucocorticoids and annexin 1 peptides.
de réir: John, C, et al.
Foilsithe / Cruthaithe: (2003)

Estrogen Promotes Pro-resolving Microglial Behavior and Phagocytic Cell Clearance Through the Actions of Annexin A1
de réir: Rodrigo Azevedo Loiola, et al.
Foilsithe / Cruthaithe: (2019-06-01)

Annexin A1 regulates hormone exocytosis through a mechanism involving actin reorganization.
de réir: McArthur, S, et al.
Foilsithe / Cruthaithe: (2009)

Annexin 1 dependent actions of glucocorticoids in the anterior pituitary gland - role of the formyl peptide receptor family
de réir: Buckingham, J, et al.
Foilsithe / Cruthaithe: (2006)

Post-translational modification plays an essential role in the translocation of annexin A1 from the cytoplasm to the cell surface.
de réir: Solito, E, et al.
Foilsithe / Cruthaithe: (2006)

Post-translational modification plays an essential role in the translocation of annexin A1 from the cytoplasm to the cell surface
de réir: Solito, E, et al.
Foilsithe / Cruthaithe: (2006)

Formyl peptide receptors and the regulation of ACTH secretion: targets for annexin A1, lipoxins, and bacterial peptides.
de réir: John, C, et al.
Foilsithe / Cruthaithe: (2007)

Gene deletion reveals roles for annexin A1 in the regulation of lipolysis and IL-6 release in epididymal adipose tissue.
de réir: Warne, J, et al.
Foilsithe / Cruthaithe: (2006)

Annexin 1-dependent actions of glucocorticoids in the anterior pituitary gland: roles of the N-terminal domain and protein kinase C.
de réir: John, C, et al.
Foilsithe / Cruthaithe: (2002)

Expression, subcellular localization and phosphorylation status of annexins 1 and 5 in human pituitary adenomas and a growth hormone-secreting carcinoma.
de réir: Mulla, A, et al.
Foilsithe / Cruthaithe: (2004)

AnnexinA6: a potential therapeutic target gene for extracellular matrix mineralization
de réir: Jie Yang, et al.
Foilsithe / Cruthaithe: (2023-09-01)

Induction of annexin-1 at transcriptional and post-transcriptional level in rat brain by methylprednisolone and the 21-aminosteroid U74389F
de réir: P. H. Voermans, et al.
Foilsithe / Cruthaithe: (1996-01-01)

Annexin A2 and Kidney Diseases
de réir: Ling Lin, et al.
Foilsithe / Cruthaithe: (2022-09-01)

Evidence from studies on co-cultures of TtT/GF and AtT20 cells that Annexin 1 acts as a paracrine or juxtacrine mediator of the early inhibitory effects of glucocorticoids on ACTH release.
de réir: Tierney, T, et al.
Foilsithe / Cruthaithe: (2003)

Expression and externalization of annexin 1 in the adrenal gland: structure and function of the adrenal gland in annexin 1-null mutant mice.
de réir: Davies, E, et al.
Foilsithe / Cruthaithe: (2007)

Expression and externalization of annexin 1 in the adrenal gland: structure and function of the adrenal gland in annexin 1-null mutant mice
de réir: Davies, E, et al.
Foilsithe / Cruthaithe: (2007)

Annexin 1: a local paracrine regulator of adrenal size and corticosterone secretion: evidence from annexin 1-null mice
de réir: Morris, J, et al.
Foilsithe / Cruthaithe: (2007)

Annexin in plants
de réir: Phang, Ing Chia
Foilsithe / Cruthaithe: (2006)

Inhibitory role of Annexin A1 in pathological bone resorption and therapeutic implications in periprosthetic osteolysis
de réir: Hend Alhasan, et al.
Foilsithe / Cruthaithe: (2022-07-01)

Annexin A1 in the nervous and ocular systems
de réir: Aijia Wang, et al.
Foilsithe / Cruthaithe: (2024-01-01)

Contribution of annexin A1 to anticancer immunosurveillance
de réir: Elisa Elena Baracco, et al.
Foilsithe / Cruthaithe: (2019-11-01)

Participation of annexin 1 in the response of Arabidopsis thaliana to lead exposure: potential for phytoremediation
de réir: Phang, Ing Chia, et al.
Foilsithe / Cruthaithe: (2009)

Annexin A2-mediated cancer progression and therapeutic resistance in nasopharyngeal carcinoma
de réir: Chang-Yu Chen, et al.
Foilsithe / Cruthaithe: (2018-03-01)

HDX-MS for Epitope Characterization of a Therapeutic ANTIBODY Candidate on the Calcium-Binding Protein Annexin-A1
de réir: Marius Gramlich, et al.
Foilsithe / Cruthaithe: (2021-03-01)