Inadequate BiP availability defines endoplasmic reticulum stress
How endoplasmic reticulum (ER) stress leads to cytotoxicity is ill-defined. Previously we showed that HeLa cells readjust homeostasis upon proteostatically driven ER stress, triggered by inducible bulk expression of secretory immunoglobulin M heavy chain (μs) thanks to the unfolded protein response...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Journal article |
| Published: |
eLife Sciences Publications
2019
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