Inadequate BiP availability defines endoplasmic reticulum stress

Inadequate BiP availability defines endoplasmic reticulum stress

How endoplasmic reticulum (ER) stress leads to cytotoxicity is ill-defined. Previously we showed that HeLa cells readjust homeostasis upon proteostatically driven ER stress, triggered by inducible bulk expression of secretory immunoglobulin M heavy chain (μs) thanks to the unfolded protein response...

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Bibliographic Details
Main Authors:	Vitale, M, Bakunts, A, Orsi, A, Lari, F, Tade, L, Danieli, A, Rato, C, Valetti, C, Sitia, R, Raimondi, A, Christianson, J, Van Anken, E
Format:	Journal article
Published:	eLife Sciences Publications 2019

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