Reduced levels of tetrahydrobiopterin in diabetic mouse model: Effects on endothelial function and nitric oxide (NO) synthase dimerisation

Reduced levels of tetrahydrobiopterin in diabetic mouse model: Effects on endothelial function and nitric oxide (NO) synthase dimerisation

Bibliográfalaš dieđut
Váldodahkkit:	Cai, S, Khoo, J, Mussa, S, Alp, N, Channon, K
Materiálatiipa:	Conference item
Almmustuhtton:	2004

Geahča maid

Endothelial nitric oxide synthase dysfunction in diabetic mice: importance of tetrahydrobiopterin in eNOS dimerisation.
Dahkki: Cai, S, et al.
Almmustuhtton: (2005)

Regulation of endothelial nitric oxide synthase (eNOS) by tetrahydrobiopterin in vascular disease
Dahkki: Alp, N, et al.
Almmustuhtton: (2004)

GTP cyclohydrolase I gene transfer augments intracellular tetrahydrobiopterin in human endothelial cells: effects on nitric oxide synthase activity, protein levels and dimerisation.
Dahkki: Cai, S, et al.
Almmustuhtton: (2002)

Regulation of endothelial nitric oxide synthase by tetrahydrobiopterin in vascular disease.
Dahkki: Alp, N, et al.
Almmustuhtton: (2004)

Endothelial tetrahydrobiopterin deficiency accelerates atherosclerotic progression by nitric oxide synthase uncoupling
Dahkki: Khoo, J, et al.
Almmustuhtton: (2005)

Tetrahydrobiopterin: regulator of endothelial nitric oxide synthase in vascular disease.
Dahkki: Channon, K
Almmustuhtton: (2004)

Nitric oxide Bioavailability is preserved in diabetes by increased endothelial tetrahydrobiopterin synthesis in targeted GTP cyclohydrolase transgenic mice
Dahkki: Alp, N, et al.
Almmustuhtton: (2003)

Tetrahydrobiopterin and nitric oxide synthase recouplers
Dahkki: Channon, KM
Almmustuhtton: (2020)

Diabetes reduces vascular tetrahydrobiopterin levels by oxidation: Insights from a GTPCH-transgenic mouse model
Dahkki: Alp, N, et al.
Almmustuhtton: (2003)

Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I overexpression.
Dahkki: Alp, N, et al.
Almmustuhtton: (2003)

Tetrahydrobiopterin deficiency uncouples nitric oxide synthase and causes pulmonary hypertension
Dahkki: Khoo, J, et al.
Almmustuhtton: (2004)

Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I over-expression
Dahkki: Alp, N, et al.
Almmustuhtton: (2003)

Prevention of hypoxia-induced pulmonary hypertension and vascular remodelling by targeting endothelial tetrahydrobiopterin-dependent nitric oxide synthase regulation
Dahkki: Khoo, J, et al.
Almmustuhtton: (2005)

Dihydrofolate reductase protects endothelial nitric oxide synthase from uncoupling in tetrahydrobiopterin deficiency.
Dahkki: Crabtree, M, et al.
Almmustuhtton: (2011)

Dihydrofolate reductase protects endothelial nitric oxide synthase from uncoupling in tetrahydrobiopterin deficiency
Dahkki: Crabtree, M, et al.
Almmustuhtton: (2011)

Tetrahydrobiopterin Prevents Lung Ischemia/reperfusion-Induced Uncoupling of Endothelial Nitric Oxide Synthase
Dahkki: Juni, R, et al.
Almmustuhtton: (2012)

Integrated redox sensor and effector functions for tetrahydrobiopterin- and glutathionylation-dependent endothelial nitric-oxide synthase uncoupling.
Dahkki: Crabtree, M, et al.
Almmustuhtton: (2013)

Nitric oxide bioactivity in ApoE -/- mice is maintained by increased endothelial tetrahydrobiopterin synthesis via targeted GTP cyclohydrolase-1 over-expression
Dahkki: Alp, N, et al.
Almmustuhtton: (2003)

Increased endothelial tetrahydrobiopterin levels by GTPCH over expression in transgenic mice prevents diabetic endothelial dysfunction
Dahkki: Alp, N, et al.
Almmustuhtton: (2003)

Adenovirus-mediated GTP cyclohydrolase I gene delivery augments tetrahydrobiopterin and restores nitric oxide synthase function in hyperglycaemic human aortic endothelial cells
Dahkki: Cai, S, et al.
Almmustuhtton: (2004)

Adenovirus-mediated GTP cyclohydrolase I gene delivery augments tetrahydrobiopterin and restores nitric oxide synthase function in hyperglycaemic human aortic endothelial cells
Dahkki: Cai, S, et al.
Almmustuhtton: (2004)

Critical role for tetrahydrobiopterin recycling by dihydrofolate reductase in regulation of endothelial nitric-oxide synthase coupling: relative importance of the de novo biopterin synthesis versus salvage pathways.
Dahkki: Crabtree, M, et al.
Almmustuhtton: (2009)

Increased endothelial tetrahydrobiopterin levels in GTPCH-transgenic mice
Dahkki: Alp, N, et al.
Almmustuhtton: (2002)

Differential Inhibition of Constitutive and Inducible Nitric Oxide Synthase in Vascular Endothelial Cells by Analogues of Tetrahydrobiopterin
Dahkki: Mueller Nicolas J, et al.
Almmustuhtton: (2002-11-01)

Recoupling the cardiac nitric oxide synthases: tetrahydrobiopterin synthesis and recycling.
Dahkki: Alkaitis, MS, et al.
Almmustuhtton: (2012)

Recoupling the cardiac nitric oxide synthases: Tetrahydrobiopterin synthesis and recycling
Dahkki: Alkaitis, MS, et al.
Almmustuhtton: (2012)

The role of nitric oxide synthase (nos) and the cofactor tetrahydrobiopterin (bh4) in diabetic cardiomyopathy
Dahkki: Duglan, D
Almmustuhtton: (2016)

P683The role of nitric oxide synthase (NOS) and its essential cofactor tetrahydrobiopterin (BH4) in diabetic cardiomyopathy.
Dahkki: Duglan, D, et al.
Almmustuhtton: (2014)

5-methyltetrahydrofolate rapidly improves endothelial function and decreases superoxide production in human vessels: effects on vascular tetrahydrobiopterin availability and endothelial nitric oxide synthase coupling.
Dahkki: Antoniades, C, et al.
Almmustuhtton: (2006)

Functional comparison of the endothelial nitric oxide synthase Glu298Asp polymorphic variants in human endothelial cells.
Dahkki: McDonald, D, et al.
Almmustuhtton: (2004)

Pivotal role for endothelial tetrahydrobiopterin in pulmonary hypertension.
Dahkki: Khoo, J, et al.
Almmustuhtton: (2005)

Tetrahydrobiopterin protects against hypertrophic heart disease independent of myocardial nitric oxide synthase coupling.
Dahkki: Hashimoto, T, et al.
Almmustuhtton: (2016)

Tetrahydrobiopterin protects against hypertrophic heart disease independent of myocardial nitric oxide synthase coupling
Dahkki: Hashimoto, T, et al.
Almmustuhtton: (2016)

Augmented BH4 by gene transfer restores nitric oxide synthase function in hyperglycemic human endothelial cells.
Dahkki: Cai, S, et al.
Almmustuhtton: (2005)

Tetrahydrobiopterin: coupling nitric oxide and redox signalling in cardiovascular disease
Dahkki: Channon, K
Almmustuhtton: (2012)

Rapid, direct effects of statin treatment on arterial redox state and nitric oxide bioavailability in human atherosclerosis via tetrahydrobiopterin-mediated endothelial nitric oxide synthase coupling.
Dahkki: Antoniades, C, et al.
Almmustuhtton: (2011)

Rapid, direct effects of statin treatment on arterial redox state and nitric oxide bioavailability in human atherosclerosis via tetrahydrobiopterin- mediated endothelial nitric oxide synthase coupling
Dahkki: Antoniades, C, et al.
Almmustuhtton: (2011)

Tetrahydrobiopterin Protects Against Hypertrophic Heart Disease Independent of Myocardial Nitric Oxide Synthase Coupling
Dahkki: Toru Hashimoto, et al.
Almmustuhtton: (2016-03-01)

Increased endothelial tetrahydrobiopterin reduces in stent stenosis in apolipoprotein E-knockout mice
Dahkki: Ali, Z, et al.
Almmustuhtton: (2007)

Statin treatment improves vascular redox state through a tetrahydrobiopterin-mediated re-coupling of endothelial nitric oxide synthase, in human atherosclerosis
Dahkki: Antoniades, C, et al.
Almmustuhtton: (2011)