Structural and functional characterisation of the group II chaperonin CCT/TRiC

Structural and functional characterisation of the group II chaperonin CCT/TRiC

<p>Cellular health is dependent on the proper folding of proteins and dysregulation of this pathway can lead to many diseases including neurodegeneration and cancer. This thesis describes efforts undertaken to characterise the mechanism by which one eukaryotic protein chaperonin, CCT/TRiC (TRi...

Fuld beskrivelse

Bibliografiske detaljer
Hovedforfatter:	Kelly, J
Andre forfattere:	Yue, W
Format:	Thesis
Sprog:	English
Udgivet:	2020
Fag:	Biochemistry

Lignende værker

Asymmetry in the function and dynamics of the cytosolic group II chaperonin CCT/TRiC.
af: Yohei Y Yamamoto, et al.
Udgivet: (2017-01-01)

Modulation of STAT3 folding and function by TRiC/CCT chaperonin.
af: Moses Kasembeli, et al.
Udgivet: (2014-04-01)

Chaperonin TRiC/CCT supports mitotic exit and entry into endocycle in Drosophila.
af: Yuya Ohhara, et al.
Udgivet: (2019-04-01)

Assembly and substrate recognition properties of human CCT subunits of the TRiC chaperonin
af: Sergeeva, Oksana A
Udgivet: (2015)

TRiC/CCT chaperonin is required for the folding and inhibitory effect of WDTC1 on adipogenesis
af: Wen-Shuai Tang, et al.
Udgivet: (2023-08-01)

Chaperonin TRiC/CCT subunit CCT7 is involved in the replication of canine parvovirus in F81 cells
af: Xia Su, et al.
Udgivet: (2024-02-01)

Chaperonin containing TCP-1 (CCT/TRiC) is a novel therapeutic and diagnostic target for neuroblastoma
af: Amanda Cox, et al.
Udgivet: (2022-09-01)

The Chaperonin TRiC/CCT Inhibitor HSF1A Protects Cells from Intoxication with Pertussis Toxin
af: Jinfang Jia, et al.
Udgivet: (2024-01-01)

Native mass spectrometry analyses of chaperonin complex TRiC/CCT reveal subunit N-terminal processing and re-association patterns
af: Miranda P. Collier, et al.
Udgivet: (2021-06-01)

Co-expression of CCT subunits hints at TRiC assembly
af: Sergeeva, Oksana A, et al.
Udgivet: (2021)

The chaperonin TRiC forms an oligomeric complex in the malaria parasite cytosol
af: Spillman, Natalie J., et al.
Udgivet: (2018)

The recruitment of TRiC chaperonin in rotavirus viroplasms correlates with virus replication
af: Janine Vetter, et al.
Udgivet: (2024-04-01)

In Vivo Function of the Chaperonin TRiC in α-Actin Folding during Sarcomere Assembly
af: Joachim Berger, et al.
Udgivet: (2018-01-01)

Structure of the human TRiC/CCT Subunit 5 associated with hereditary sensory neuropathy
af: Jose H. Pereira, et al.
Udgivet: (2017-06-01)

Structure of the human TRiC/CCT Subunit 5 associated with hereditary sensory neuropathy
af: Pereira, Jose H., et al.
Udgivet: (2018)

The HIF prolyl hydroxylase PHD3 is a potential substrate of the TRiC chaperonin.
af: Masson, N, et al.
Udgivet: (2004)

Involvement of T-complex protein 1-ring complex/chaperonin containing T-complex protein 1 (TRiC/CCT) in retrograde axonal transport through tau phosphorylation
af: Xu-Qiao Chen
Udgivet: (2019-01-01)

The role of molecular chaperone CCT/TRiC in translation elongation: A literature review
af: Yueyue Que, et al.
Udgivet: (2024-04-01)

A Gradient of ATP Affinities Generates an Asymmetric Power Stroke Driving the Chaperonin TRIC/CCT Folding Cycle
af: Stefanie Reissmann, et al.
Udgivet: (2012-10-01)

Mob4-dependent STRIPAK involves the chaperonin TRiC to coordinate myofibril and microtubule network growth.
af: Joachim Berger, et al.
Udgivet: (2022-06-01)

Systematic Characterization of Expression Profiles and Prognostic Values of the Eight Subunits of the Chaperonin TRiC in Breast Cancer
af: Wen-Xiu Xu, et al.
Udgivet: (2021-03-01)

Usher syndrome proteins ADGRV1 (USH2C) and CIB2 (USH1J) interact and share a common interactome containing TRiC/CCT-BBS chaperonins
af: Joshua Linnert, et al.
Udgivet: (2023-06-01)

A Direct Regulatory Interaction between Chaperonin TRiC and Stress-Responsive Transcription Factor HSF1
af: Daniel W. Neef, et al.
Udgivet: (2014-11-01)

The Molecular Chaperone CCT/TRiC: An Essential Component of Proteostasis and a Potential Modulator of Protein Aggregation
af: Julie Grantham
Udgivet: (2020-03-01)

Human TRiC complex purified from HeLa cells contains all eight CCT subunits and is active in vitro
af: Knee, Kelly M., et al.
Udgivet: (2014)

A structural vista of phosducin-like PhLP2A-chaperonin TRiC cooperation during the ATP-driven folding cycle
af: Junsun Park, et al.
Udgivet: (2024-02-01)

Folding for the Immune Synapse: CCT Chaperonin and the Cytoskeleton
af: Noa Beatriz Martín-Cófreces, et al.
Udgivet: (2021-04-01)

Structural and functional analysis of the role of the chaperonin CCT in mTOR complex assembly
af: Jorge Cuéllar, et al.
Udgivet: (2019-06-01)

Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM
af: Caixuan Liu, et al.
Udgivet: (2023-05-01)

Crystal structure of the open conformation of the mammalian chaperonin CCT in complex with tubulin.
af: Muñoz, I, et al.
Udgivet: (2011)

The TRiC/CCT chaperone is implicated in Alzheimer's disease based on patient GWAS and an RNAi screen in Aβ-expressing Caenorhabditis elegans.
af: Eleonora Khabirova, et al.
Udgivet: (2014-01-01)

TRiC/CCT Complex, a Binding Partner of NS1 Protein, Supports the Replication of Zika Virus in Both Mammalians and Mosquitoes
af: Yuchen Wang, et al.
Udgivet: (2020-05-01)

TRiC’s tricks inhibit huntingtin aggregation
af: Sarah H Shahmoradian, et al.
Udgivet: (2013-07-01)

The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function
af: Bergithe E. Oftedal, et al.
Udgivet: (2021-06-01)

The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function
af: Oftedal, BE, et al.
Udgivet: (2021)

The malaria parasite chaperonin containing TCP-1 (CCT) complex: Data integration with other CCT proteomes
af: Mark D. Wilkinson, et al.
Udgivet: (2022-12-01)

The Role of TRiC-enhanced Actin Folding in Leber Congenital Amaurosis
af: Silke Berger, et al.
Udgivet: (2023-02-01)

Chaperonin CCT controls extracellular vesicle production and cell metabolism through kinesin dynamics
af: Amelia Rojas‐Gómez, et al.
Udgivet: (2023-06-01)

Association of the influenza virus RNA polymerase subunit PB2 with the host chaperonin CCT.
af: Fislová, T, et al.
Udgivet: (2010)

Ginkgolide B targets and inhibits creatine kinase B to regulate the CCT/TRiC-SK1 axis and exerts pro-angiogenic activity in middle cerebral artery occlusion mice
af: Jiale Zhu, et al.
Udgivet: (2022-06-01)