In vitro generation of mature human osteoclasts.

Mononuclear precursors of human osteoclasts are found in the CD14(+) monocyte fraction of circulating peripheral blood mononuclear cells (PBMCs). It is possible to generate osteoclasts in vitro from PBMCs cultured with macrophage colony-stimulating factor and receptor activator for nuclear factor κB...

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Autori principali: Hemingway, F, Cheng, X, Knowles, H, Estrada, F, Gordon, S, Athanasou, N
Natura: Journal article
Lingua:English
Pubblicazione: 2011