Angiocrine signals regulate quiescence and therapy resistance in bone metastasis

Bone provides supportive microenvironments for hematopoietic stem cells (HSCs) and mesenchymal stem cells (MSCs) and is a frequent site of metastasis. While incidences of bone metastases increase with age, the properties of the bone marrow microenvironment that regulate dormancy and reactivation of...

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Những tác giả chính: Singh, A, Veeriah, V, Xi, P, Labella, R, Chen, J, Romeo, S, Ramasamy, S, Kusumbe, A
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: American Society for Clinical Investigation 2019