Sex ratio of infectious mononucleosis and possible relevance to multiple sclerosis.

Infectious mononucleosis (IM) is associated with the risk of developing multiple sclerosis (MS). Using databases of hospital admissions for England (1999-2005), we investigated the female-to-male ratios (FMRs) for admission to hospital for IM and MS stratified by age. Males were more frequently admi...

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Asıl Yazarlar: Ramagopalan, S, Giovannoni, G, Yeates, D, Seagroatt, V, Goldacre, M
Materyal Türü: Journal article
Dil:English
Baskı/Yayın Bilgisi: 2013
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author Ramagopalan, S
Giovannoni, G
Yeates, D
Seagroatt, V
Goldacre, M
author_facet Ramagopalan, S
Giovannoni, G
Yeates, D
Seagroatt, V
Goldacre, M
author_sort Ramagopalan, S
collection OXFORD
description Infectious mononucleosis (IM) is associated with the risk of developing multiple sclerosis (MS). Using databases of hospital admissions for England (1999-2005), we investigated the female-to-male ratios (FMRs) for admission to hospital for IM and MS stratified by age. Males were more frequently admitted for IM for all age groups apart from ages 10-14 (FMR 1.50; 95% confidence interval (CI) 1.36-1.64) and, borderline significantly, at ages 15-19 (FMR 1.03, 95% CI 0.99-1.08). This intriguing aspect of IM epidemiology in adolescence, the atypical female excess, may be linked to the sex ratio of MS, where females predominate from adolescence.
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spelling oxford-uuid:c6d5b1b6-1d0d-4ae2-9d3b-ba821bf3ad3c2022-03-27T06:40:41ZSex ratio of infectious mononucleosis and possible relevance to multiple sclerosis.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:c6d5b1b6-1d0d-4ae2-9d3b-ba821bf3ad3cEnglishSymplectic Elements at Oxford2013Ramagopalan, SGiovannoni, GYeates, DSeagroatt, VGoldacre, MInfectious mononucleosis (IM) is associated with the risk of developing multiple sclerosis (MS). Using databases of hospital admissions for England (1999-2005), we investigated the female-to-male ratios (FMRs) for admission to hospital for IM and MS stratified by age. Males were more frequently admitted for IM for all age groups apart from ages 10-14 (FMR 1.50; 95% confidence interval (CI) 1.36-1.64) and, borderline significantly, at ages 15-19 (FMR 1.03, 95% CI 0.99-1.08). This intriguing aspect of IM epidemiology in adolescence, the atypical female excess, may be linked to the sex ratio of MS, where females predominate from adolescence.
spellingShingle Ramagopalan, S
Giovannoni, G
Yeates, D
Seagroatt, V
Goldacre, M
Sex ratio of infectious mononucleosis and possible relevance to multiple sclerosis.
title Sex ratio of infectious mononucleosis and possible relevance to multiple sclerosis.
title_full Sex ratio of infectious mononucleosis and possible relevance to multiple sclerosis.
title_fullStr Sex ratio of infectious mononucleosis and possible relevance to multiple sclerosis.
title_full_unstemmed Sex ratio of infectious mononucleosis and possible relevance to multiple sclerosis.
title_short Sex ratio of infectious mononucleosis and possible relevance to multiple sclerosis.
title_sort sex ratio of infectious mononucleosis and possible relevance to multiple sclerosis
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