Meta-analysis of gene-level tests for rare variant association.

Meta-analysis of gene-level tests for rare variant association.

Taispeáin leaganacha eile (1)

The majority of reported complex disease associations for common genetic variants have been identified through meta-analysis, a powerful approach that enables the use of large sample sizes while protecting against common artifacts due to population structure and repeated small-sample analyses sharin...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí:	Liu, D, Peloso, G, Zhan, X, Holmen, O, Zawistowski, M, Feng, S, Nikpay, M, Auer, P, Goel, A, Zhang, H, Peters, U, Farrall, M, Orho-Melander, M, Kooperberg, C, McPherson, R, Watkins, H, Willer, C, Hveem, K, Melander, O, Kathiresan, S, Abecasis, G
Formáid:	Journal article
Teanga:	English
Foilsithe / Cruthaithe:	2014

Míreanna comhchosúla

Meta-analysis of gene-level tests for rare variant association
de réir: Liu, D, et al.
Foilsithe / Cruthaithe: (2014)

Exome sequencing and directed clinical phenotyping diagnose cholesterol ester storage disease presenting as autosomal recessive hypercholesterolemia.
de réir: Stitziel, N, et al.
Foilsithe / Cruthaithe: (2013)

Exome Sequencing and Directed Clinical Phenotyping Diagnose Cholesterol Ester Storage Disease Presenting as Autosomal Recessive Hypercholesterolemia
de réir: Stitziel, N, et al.
Foilsithe / Cruthaithe: (2013)

New insights into impaired muscle glycogen synthesis.
de réir: Leif Groop, et al.
Foilsithe / Cruthaithe: (2008-01-01)

Variants in the calpain-10 gene predispose to insulin resistance and elevated free fatty acid levels.
de réir: Orho-Melander, M, et al.
Foilsithe / Cruthaithe: (2002)

Functional characterisation of the glucokinase regulatory protein gene variant P446L shows diminished regulation by fructose-6 phosphate resulting in increased glucokinase activity
de réir: Beer, N, et al.
Foilsithe / Cruthaithe: (2009)

Plasma Metabolome Predicts Aortic Stiffness and Future Risk of Coronary Artery Disease and Mortality After 23 Years of Follow‐Up in the General Population
de réir: Filip Ottosson, et al.
Foilsithe / Cruthaithe: (2024-05-01)

Putative role for the calpain 10 gene in free fatty acid metabolism.
de réir: Orho-Melander, M, et al.
Foilsithe / Cruthaithe: (2001)

Interaction between blood pressure and genetic risk score for bladder cancer, and risk of urothelial carcinoma in men
de réir: Stanley Teleka, et al.
Foilsithe / Cruthaithe: (2022-10-01)

Characterization of the annexin I gene and evaluation of its role in type 2 diabetes.
de réir: Lindgren, C, et al.
Foilsithe / Cruthaithe: (2001)

A genome-wide search for susceptiblity loci to the metabolic syndrome in the Botnia study
de réir: Wieslander, J, et al.
Foilsithe / Cruthaithe: (2000)

Genome wide scan and fine-mapping for early onset primary hypertension susceptibility loci in Scandinavian families
de réir: Wowern, F, et al.
Foilsithe / Cruthaithe: (2002)

Biological, clinical and population relevance of 95 loci for blood lipids.
de réir: Teslovich, T, et al.
Foilsithe / Cruthaithe: (2010)

Convergence of biomarkers and risk factor trait loci of coronary artery disease at 3p21.31 and HLA region
de réir: Majid Nikpay, et al.
Foilsithe / Cruthaithe: (2021-02-01)

USE OF ENCODE DATA TO IDENTIFY PUTATIVE FUNCTIONAL VARIANTS IN CORONARY ARTERY DISEASE GWAS
de réir: Goel, A, et al.
Foilsithe / Cruthaithe: (2014)

A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study
de réir: Burtt Nöel P, et al.
Foilsithe / Cruthaithe: (2007-09-01)

A healthy dietary metabolic signature is associated with a lower risk for type 2 diabetes and coronary artery disease
de réir: Einar Smith, et al.
Foilsithe / Cruthaithe: (2022-04-01)

A prospective study of dietary and supplemental zinc intake and risk of type 2 diabetes depending on genetic variation in SLC30A8
de réir: Isabel Drake, et al.
Foilsithe / Cruthaithe: (2017-10-01)

Very short sleep duration reveals a proteomic fingerprint that is selectively associated with incident diabetes mellitus but not with incident coronary heart disease: a cohort study
de réir: Thomas Svensson, et al.
Foilsithe / Cruthaithe: (2024-04-01)

The P446L variant in GCKR associated with fasting plasma glucose and triglyceride levels exerts its effect through increased glucokinase activity in liver.
de réir: Beer, N, et al.
Foilsithe / Cruthaithe: (2009)

Circulating protein biomarkers predict incident hypertensive heart failure independently of N‐terminal pro‐B‐type natriuretic peptide levels
de réir: Celine Fernandez, et al.
Foilsithe / Cruthaithe: (2020-08-01)

Blood pressure and bladder cancer risk in men by use of survival analysis and in interaction with NAT2 genotype, and by Mendelian randomization analysis.
de réir: Stanley Teleka, et al.
Foilsithe / Cruthaithe: (2020-01-01)

Manhattan++: displaying genome-wide association summary statistics with multiple annotation layers
de réir: Grace, C, et al.
Foilsithe / Cruthaithe: (2019)

Elevated soluble LOX-1 predicts risk of first-time myocardial infarction
de réir: Alexandru Schiopu, et al.
Foilsithe / Cruthaithe: (2023-12-01)

Lifestyle and genetic risk of chronic liver disease in metabolically healthy and unhealthy individuals from the general population
de réir: Isabel Drake, et al.
Foilsithe / Cruthaithe: (2024-08-01)

Dimethylguanidino Valerate: A Lifestyle‐Related Metabolite Associated With Future Coronary Artery Disease and Cardiovascular Mortality
de réir: Filip Ottosson, et al.
Foilsithe / Cruthaithe: (2019-10-01)

A genome wide scan for early onset primary hypertension in Scandinavians.
de réir: von Wowern, F, et al.
Foilsithe / Cruthaithe: (2003)

Understanding the Function of a Locus Using the Knowledge Available at Single-Nucleotide Polymorphisms
de réir: Majid Nikpay, et al.
Foilsithe / Cruthaithe: (2021-12-01)

Genetic Variants in Lp(a) Lipoprotein and Coronary Disease REPLY
de réir: Farrall, M, et al.
Foilsithe / Cruthaithe: (2010)

Genetic variation in the fat mass and obesity-associated gene (FTO) in association with food preferences in healthy adults
de réir: Louise Brunkwall, et al.
Foilsithe / Cruthaithe: (2013-04-01)

LPA NULL MUTATION GENOTYPING AND QPCR ANALYSIS REFINE KRINGLE ISOFORM ANALYSIS OF LP(A) LEVELS
de réir: Kyriakou, T, et al.
Foilsithe / Cruthaithe: (2014)

Isotopes effects on reaction rates/
de réir: 299827 Melander, Lars C. S.
Foilsithe / Cruthaithe: (1960)

Ultima Ratio in European Criminal Law
de réir: Sakari Melander
Foilsithe / Cruthaithe: (2012-05-01)

Kriminaliseringsprinciper och förutsättningar för begränsning av grundläggande fri- och rättigheter
de réir: Sakari Melander
Foilsithe / Cruthaithe: (2002-12-01)

Att göra högre studier tillgängligliga – ett lärarperspektiv
de réir: Stina Melander
Foilsithe / Cruthaithe: (2020-11-01)

Ultima Ratio in European Criminal Law
de réir: Sakari Melander
Foilsithe / Cruthaithe: (2013-01-01)

Genetic susceptibility to coronary artery disease: from promise to progress.
de réir: Watkins, H, et al.
Foilsithe / Cruthaithe: (2006)

The Gly82Ser polymorphism in the receptor for advanced glycation endproducts increases the risk for coronary events in the general population
de réir: Helena Grauen Larsen, et al.
Foilsithe / Cruthaithe: (2024-05-01)

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals
de réir: Ehret, G, et al.
Foilsithe / Cruthaithe: (2016)

Plasma HDL cholesterol and risk of myocardial infarction: A mendelian randomisation study
de réir: Voight, B, et al.
Foilsithe / Cruthaithe: (2012)