Assessing the viral fitness of oseltamivir-resistant influenza viruses in ferrets, using a competitive-mixtures model.

Assessing the viral fitness of oseltamivir-resistant influenza viruses in ferrets, using a competitive-mixtures model.

To determine the relative fitness of oseltamivir-resistant strains compared to susceptible wild-type viruses, we combined mathematical modeling and statistical techniques with a novel in vivo "competitive-mixtures" experimental model. Ferrets were coinfected with either pure populations (1...

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Những tác giả chính:	Hurt, A, Nor'e, S, McCaw, J, Fryer, H, Mosse, J, Mclean, A, Barr, I
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	2010

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