Two-stage candidate gene study of chromosome 3p demonstrates an association between nonsynonymous variants in the MST1R gene and Crohn's disease.

Two-stage candidate gene study of chromosome 3p demonstrates an association between nonsynonymous variants in the MST1R gene and Crohn's disease.

BACKGROUND: Genomewide linkage studies identified chromosome 3p21 as an IBD locus. Genomewide association studies have supported this locus and the Wellcome Trust Case Control Consortium (WTCCC) study narrowed it to a 0.6 Mb region. Our objectives were to perform a 2-stage candidate gene associatio...

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Bibliographic Details
Main Authors:	Beckly, J, Hancock, L, Geremia, A, Cummings, JR, Morris, A, Cooney, R, Pathan, S, Guo, C, Jewell, D
Format:	Journal article
Language:	English
Published:	2008

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