Epigenetic programming defines haematopoietic stem cell fate restriction

Epigenetic programming defines haematopoietic stem cell fate restriction

Haematopoietic stem cells (HSCs) are multipotent, but individual HSCs can show restricted lineage output in vivo. Currently, the molecular mechanisms and physiological role of HSC fate restriction remain unknown. Here we show that lymphoid fate is epigenetically but not transcriptionally primed in H...

Bibliografski detalji
Glavni autori:	Meng, Y, de Teixeira Carrelha, J, Drissen, R, Ren, X, Zhang, B, Gambardella, A, Valletta, S, Thongjuea, S, Jacobsen, SE, Nerlov, C
Format:	Journal article
Jezik:	English
Izdano:	Springer Nature 2023

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