Epigenetic programming defines haematopoietic stem cell fate restriction
Haematopoietic stem cells (HSCs) are multipotent, but individual HSCs can show restricted lineage output in vivo. Currently, the molecular mechanisms and physiological role of HSC fate restriction remain unknown. Here we show that lymphoid fate is epigenetically but not transcriptionally primed in H...
Автори: | , , , , , , , , , |
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Формат: | Journal article |
Мова: | English |
Опубліковано: |
Springer Nature
2023
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