Acanthosis nigricans, insulin resistance and cutaneous virilism.
Thirteen patients with the syndrome of acanthosis nigricans and insulin resistance are described. They all had a combination of dermatoses related to hyperandrogenism (cutaneous virilism): hirsuties (II), acne vulgaris (6), hidradenitis suppurativa (5) and androgenic alopecia (4). In addition, 9 out...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
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1988
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| _version_ | 1797094071146119168 |
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| author | Barth, J Ng, L Wojnarowska, F Dawber, R |
| author_facet | Barth, J Ng, L Wojnarowska, F Dawber, R |
| author_sort | Barth, J |
| collection | OXFORD |
| description | Thirteen patients with the syndrome of acanthosis nigricans and insulin resistance are described. They all had a combination of dermatoses related to hyperandrogenism (cutaneous virilism): hirsuties (II), acne vulgaris (6), hidradenitis suppurativa (5) and androgenic alopecia (4). In addition, 9 out of 13 had keratosis pilaris. The patients had raised fasting plasma insulin levels compared with matched normal controls (P less than 0.01) and increased insulin resistance (P less than 0.02). Insulin resistance correlated with total serum testosterone (rs = 0.65; P less than 0.02). |
| first_indexed | 2024-03-07T04:09:03Z |
| format | Journal article |
| id | oxford-uuid:c7345bcb-374f-4272-99a1-6b8724aa404f |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T04:09:03Z |
| publishDate | 1988 |
| record_format | dspace |
| spelling | oxford-uuid:c7345bcb-374f-4272-99a1-6b8724aa404f2022-03-27T06:43:20ZAcanthosis nigricans, insulin resistance and cutaneous virilism.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:c7345bcb-374f-4272-99a1-6b8724aa404fEnglishSymplectic Elements at Oxford1988Barth, JNg, LWojnarowska, FDawber, RThirteen patients with the syndrome of acanthosis nigricans and insulin resistance are described. They all had a combination of dermatoses related to hyperandrogenism (cutaneous virilism): hirsuties (II), acne vulgaris (6), hidradenitis suppurativa (5) and androgenic alopecia (4). In addition, 9 out of 13 had keratosis pilaris. The patients had raised fasting plasma insulin levels compared with matched normal controls (P less than 0.01) and increased insulin resistance (P less than 0.02). Insulin resistance correlated with total serum testosterone (rs = 0.65; P less than 0.02). |
| spellingShingle | Barth, J Ng, L Wojnarowska, F Dawber, R Acanthosis nigricans, insulin resistance and cutaneous virilism. |
| title | Acanthosis nigricans, insulin resistance and cutaneous virilism. |
| title_full | Acanthosis nigricans, insulin resistance and cutaneous virilism. |
| title_fullStr | Acanthosis nigricans, insulin resistance and cutaneous virilism. |
| title_full_unstemmed | Acanthosis nigricans, insulin resistance and cutaneous virilism. |
| title_short | Acanthosis nigricans, insulin resistance and cutaneous virilism. |
| title_sort | acanthosis nigricans insulin resistance and cutaneous virilism |
| work_keys_str_mv | AT barthj acanthosisnigricansinsulinresistanceandcutaneousvirilism AT ngl acanthosisnigricansinsulinresistanceandcutaneousvirilism AT wojnarowskaf acanthosisnigricansinsulinresistanceandcutaneousvirilism AT dawberr acanthosisnigricansinsulinresistanceandcutaneousvirilism |