Pharmacodynamic and pharmacokinetic markers for anti-angiogenic cancer therapy: Implications for dosing and selection of patients.
Angiogenesis is integral to tumour growth and invasion, and is a key target for cancer therapeutics. However, for many of the licensed indications, only a modest clinical benefit has been observed for both monoclonal antibody and small-molecule tyrosine kinase inhibitor anti-angiogenic therapy. Pre-...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Springer
2017
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