Homocysteine and coronary heart disease: meta-analysis of MTHFR case-control studies, avoiding publication bias.
BACKGROUND: Moderately elevated blood levels of homocysteine are weakly correlated with coronary heart disease (CHD) risk, but causality remains uncertain. When folate levels are low, the TT genotype of the common C677T polymorphism (rs1801133) of the methylene tetrahydrofolate reductase gene (MTHFR...
Main Authors: | Clarke, R, Bennett, D, Parish, S, Verhoef, P, Dötsch-Klerk, M, Lathrop, M, Xu, P, Nordestgaard, BG, Holm, H, Hopewell, J, Saleheen, D, Tanaka, T, Anand, S, Chambers, J, Kleber, M, Ouwehand, W, Yamada, Y, Elbers, C, Peters, B, Stewart, A, Reilly, M, Thorand, B, Yusuf, S, Engert, J, Assimes, T, Kooner, J, Danesh, J, Watkins, H, Samani, N, Collins, R, Peto, R |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2012
|
Similar Items
-
Homocysteine, MTHFR and risk of venous thrombosis: a meta-analysis of published epidemiological studies.
by: Den Heijer, M, et al.
Published: (2005) -
MTHFR 677C-->T polymorphism and risk of coronary heart disease: a meta-analysis.
by: Klerk, M, et al.
Published: (2002) -
A Genome-Wide Association Study of Risk of Coronary Artery Disease in European and South Asian Populations
by: Hopewell, J, et al.
Published: (2010) -
Evaluation of methylenetetrahydrofolate reductase (MTHFR) activity and the levels of homocysteine and malondialdehyde (MDA) in the serum of women with preeclampsia
by: Sahar Mazloomi, et al.
Published: (2020-10-01) -
Investigation of the Association of Homocysteine and MTHFR Polymorphisms and Treatment Options in Parkinson’s Disease in Central Anatolian Region*
by: Ramazan Emre, et al.
Published: (2015-12-01)