Homocysteine and coronary heart disease: meta-analysis of MTHFR case-control studies, avoiding publication bias.

Homocysteine and coronary heart disease: meta-analysis of MTHFR case-control studies, avoiding publication bias.

BACKGROUND: Moderately elevated blood levels of homocysteine are weakly correlated with coronary heart disease (CHD) risk, but causality remains uncertain. When folate levels are low, the TT genotype of the common C677T polymorphism (rs1801133) of the methylene tetrahydrofolate reductase gene (MTHFR...

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Bibliographic Details
Main Authors: Clarke, R, Bennett, D, Parish, S, Verhoef, P, Dötsch-Klerk, M, Lathrop, M, Xu, P, Nordestgaard, BG, Holm, H, Hopewell, J, Saleheen, D, Tanaka, T, Anand, S, Chambers, J, Kleber, M, Ouwehand, W, Yamada, Y, Elbers, C, Peters, B, Stewart, A, Reilly, M, Thorand, B, Yusuf, S, Engert, J, Assimes, T, Kooner, J, Danesh, J, Watkins, H, Samani, N, Collins, R, Peto, R
Format: Journal article
Language:English
Published: 2012

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