Proliferative capacity of epitope-specific CD8 T-cell responses is inversely related to viral load in chronic human immunodeficiency virus type 1 infection.

The relationship between the function of human immunodeficiency virus (HIV)-specific CD8 T-cell responses and viral load has not been defined. In this study, we used a panel of major histocompatibility complex class I tetramers to examine responses to frequently targeted CD8 T-cell epitopes in a lar...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Day, C, Kiepiela, P, Leslie, A, van der Stok, M, Nair, K, Ismail, N, Honeyborne, I, Crawford, H, Coovadia, H, Goulder, P, Walker, B, Klenerman, P
Format: Journal article
Język:English
Wydane: 2007