Proliferative capacity of epitope-specific CD8 T-cell responses is inversely related to viral load in chronic human immunodeficiency virus type 1 infection.
The relationship between the function of human immunodeficiency virus (HIV)-specific CD8 T-cell responses and viral load has not been defined. In this study, we used a panel of major histocompatibility complex class I tetramers to examine responses to frequently targeted CD8 T-cell epitopes in a lar...
Автори: | Day, C, Kiepiela, P, Leslie, A, van der Stok, M, Nair, K, Ismail, N, Honeyborne, I, Crawford, H, Coovadia, H, Goulder, P, Walker, B, Klenerman, P |
---|---|
Формат: | Journal article |
Мова: | English |
Опубліковано: |
2007
|
Схожі ресурси
Схожі ресурси
-
Control of human immunodeficiency virus type 1 is associated with HLA-B*13 and targeting of multiple gag-specific CD8+ T-cell epitopes.
за авторством: Honeyborne, I, та інші
Опубліковано: (2007) -
Compensatory mutation partially restores fitness and delays reversion of escape mutation within the immunodominant HLA-B*5703-restricted Gag epitope in chronic human immunodeficiency virus type 1 infection.
за авторством: Crawford, H, та інші
Опубліковано: (2007) -
Compensatory mutation partially restores fitness and delays reversion of escape mutation within the immunodominant HLA-B*5703-restrieted gag epitope in chronic human immunodeficiency virus type 1 infection (vol 81, pg 8346, 2007)
за авторством: Crawford, H, та інші
Опубліковано: (2008) -
HIV-1 Escape from an HLA-B*13-Restricted Gag Epitope Affects the Gag-Pol Frameshift Stem-loop and Reduces Viral Fitness
за авторством: Prado, J, та інші
Опубліковано: (2008) -
Immunodominant HIV-1 Cd4+ T cell epitopes in chronic untreated clade C HIV-1 infection.
за авторством: Ramduth, D, та інші
Опубліковано: (2009)