Characterization of a novel cytotoxic cell-penetrating peptide derived from p14ARF protein.

Characterization of a novel cytotoxic cell-penetrating peptide derived from p14ARF protein.

The tumor suppressor p14ARF is widely deregulated in many types of cancers and is believed to function as a failsafe mechanism, inhibiting proliferation and inducing apoptosis as cellular response to a high oncogene load. We have found that a 22-amino-acid-long peptide derived from the N-terminal pa...

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Bibliografiske detaljer
Main Authors:	Johansson, H, El-Andaloussi, S, Holm, T, Mäe, M, Jänes, J, Maimets, T, Langel, U
Format:	Journal article
Sprog:	English
Udgivet:	2008

Lignende værker

Cell-penetrating peptides: mechanisms and applications.
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Distinct uptake routes of cell-penetrating peptide conjugates.
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Cellular internalization kinetics of (luciferin-)cell-penetrating peptide conjugates.
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Applications of Cell-Penetrating Peptides for Tumor Targeting and Future Cancer Therapies
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