Notch receptor-ligand binding and activation: insights from molecular studies.

Notch receptor-ligand binding and activation: insights from molecular studies.

Čájet eará veršuvnnaid (1)

The Notch receptor is part of a core signalling pathway which is highly conserved in all metazoan species. It is required for various cell fate decisions at multiple stages of development and in the adult organism, with dysregulation of the pathway associated with genetic and acquired diseases inclu...

Bibliográfalaš dieđut
Váldodahkkit:	Chillakuri, C, Sheppard, D, Lea, S, Handford, P
Materiálatiipa:	Journal article
Giella:	English
Almmustuhtton:	2012

Geahča maid

Notch receptor-ligand binding and activation: Insights from molecular studies
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Almmustuhtton: (2012)

Structural analysis uncovers lipid-binding properties of Notch ligands.
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Almmustuhtton: (2013)

Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands
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Almmustuhtton: (2017)

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Dahkki: Handford, PA, et al.
Almmustuhtton: (2018)

Structural Analysis Uncovers Lipid-Binding Properties of Notch Ligands
Dahkki: Chandramouli R. Chillakuri, et al.
Almmustuhtton: (2013-11-01)

Molecular basis for Jagged-1/Serrate ligand recognition by the Notch receptor.
Dahkki: Whiteman, P, et al.
Almmustuhtton: (2013)

Structural and functional properties of the human notch-1 ligand binding region.
Dahkki: Hambleton, S, et al.
Almmustuhtton: (2004)

Examining How O-Fucose and O-Glucose Glycans Affect Notch-Ligand Binding
Dahkki: Takeuchi, H, et al.
Almmustuhtton: (2010)

The Role of Intracellular Trafficking of Notch Receptors in Ligand-Independent Notch Activation
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Almmustuhtton: (2021-09-01)

Notch receptor-ligand binding facilitates extracellular vesicle-mediated neuron-to-neuron communication
Dahkki: Yi-Zhi Wang, et al.
Almmustuhtton: (2024-02-01)

Non-linear and flexible regions of the human Notch-1 extracellular domain revealed by high-resolution structural studies
Dahkki: Redfield, C, et al.
Almmustuhtton: (2016)

Differential expression of Notch receptors and their ligands in desmoplastic ameloblastoma
Dahkki: Siar, C.H., et al.
Almmustuhtton: (2010)

Protocol for Notch-ligand Binding Assays Using Dynabeads
Dahkki: Shogo Sawaguchi, et al.
Almmustuhtton: (2017-10-01)

Notch Ligand Binding Assay Using Flow Cytometry
Dahkki: Shweta Varshney, et al.
Almmustuhtton: (2017-12-01)

Characterising the Notch-ligand binding interaction, and its modulation by glycosylation
Dahkki: Taylor, P, et al.
Almmustuhtton: (2012)

Diversity in Notch ligand-receptor signaling interactions
Dahkki: Rachael Kuintzle, et al.
Almmustuhtton: (2025-01-01)

Molecular and cellular analysis of the membrane binding C2 domain of Notch ligands in health and disease
Dahkki: Meng, Y
Almmustuhtton: (2021)

Delta/Notch-Like EGF-Related Receptor (DNER) Is Not a Notch Ligand.
Dahkki: Maxwell Greene, et al.
Almmustuhtton: (2016-01-01)

Cis-interactions between Notch and its ligands block ligand-independent Notch activity
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Almmustuhtton: (2014-12-01)

The conserved C2 phospholipid-binding domain in Delta contributes to robust Notch signalling
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Almmustuhtton: (2021)

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Almmustuhtton: (2024-07-01)

Structural insight into the ligand binding mechanism of aryl hydrocarbon receptor
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Almmustuhtton: (2022-10-01)

Insights into intercellular receptor-ligand binding kinetics in cell communication
Dahkki: Chenyi An, et al.
Almmustuhtton: (2022-06-01)

A Review of Notch Processing With New Insights Into Ligand-Independent Notch Signaling in T-Cells
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Almmustuhtton: (2018-06-01)

Glycosylation influences the ligand binding activities of mannose receptor.
Dahkki: Su, Y, et al.
Almmustuhtton: (2005)

A new model of Notch signalling: Control of Notch receptor cis-inhibition via Notch ligand dimers.
Dahkki: Daipeng Chen, et al.
Almmustuhtton: (2023-01-01)

The Notch Signaling Pathway: Mechanistic Insights in Health and Disease
Dahkki: Yao Meng, et al.
Almmustuhtton: (2024-03-01)

Mutual inactivation of Notch receptors and ligands facilitates developmental patterning.
Dahkki: David Sprinzak, et al.
Almmustuhtton: (2011-06-01)

PyPLIF HIPPOS-Assisted Prediction of Molecular Determinants of Ligand Binding to Receptors
Dahkki: Enade P. Istyastono, et al.
Almmustuhtton: (2021-04-01)

AIP4/Itch regulates Notch receptor degradation in the absence of ligand.
Dahkki: Patricia Chastagner, et al.
Almmustuhtton: (2008-07-01)

Editorial: Molecular Insights Into Ligand-Receptor Interactions on the Cell Surface
Dahkki: Laura Marchetti, et al.
Almmustuhtton: (2022-05-01)

Molecular insights into ligand recognition and activation of chemokine receptors CCR2 and CCR3
Dahkki: Zhehua Shao, et al.
Almmustuhtton: (2022-05-01)

Role of Notch ligands in tumour angiogenesis
Dahkki: Oon, C
Almmustuhtton: (2011)

Molecular dynamics simulations of the ligand-binding domain of an N-methyl-D-aspartate receptor.
Dahkki: Kaye, S, et al.
Almmustuhtton: (2006)

Derangement model of ligand-receptor binding
Dahkki: Williams Mobolaji
Almmustuhtton: (2022-08-01)

Scavenger receptors: diverse activities and promiscuous binding of polyanionic ligands
Dahkki: Platt, N, et al.
Almmustuhtton: (1998)

Insights into ligand binding to PreQ1 Riboswitch Aptamer from molecular dynamics simulations.
Dahkki: Zhou Gong, et al.
Almmustuhtton: (2014-01-01)

The Molecular Determinants of Small-Molecule Ligand Binding at P2X Receptors
Dahkki: Gaia Pasqualetto, et al.
Almmustuhtton: (2018-02-01)

Exploring Flexibility of Progesterone Receptor Ligand Binding Domain Using Molecular Dynamics.
Dahkki: Liangzhen Zheng, et al.
Almmustuhtton: (2016-01-01)

Insights into the ligand binding specificity of SREC‐II (scavenger receptor expressed by endothelial cells)
Dahkki: Catherine Wicker‐Planquart, et al.
Almmustuhtton: (2021-10-01)