Interleukin-1 gene cluster polymorphisms and susceptibility to clinical malaria in a Gambian case-control study.

Interleukin-1 (IL1) is a potent endogenous pyrogen and inducer of the acute phase response, and these innate immune responses are an important part of the human host's initial reaction to infection by the malaria parasite. In addition, several single-nucleotide polymorphisms (SNPs) in this regi...

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Main Authors: Walley, A, Aucan, C, Kwiatkowski, D, Hill, A
格式: Journal article
语言:English
出版: 2004