The lymphocyte function-associated antigen-1 receptor costimulates plasma membrane Ras via phospholipase D2.
Ras activation as a consequence of antigen receptor (T-cell receptor; TCR) engagement on T lymphocytes is required for T-cell development, selection and function. Lymphocyte function-associated antigen-1 (LFA-1) mediates lymphocyte adhesion, stabilization of the immune synapse and bidirectional sign...
প্রধান লেখক: | Mor, A, Campi, G, Du, G, Zheng, Y, Foster, D, Dustin, M, Philips, MR |
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বিন্যাস: | Journal article |
ভাষা: | English |
প্রকাশিত: |
2007
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অনুরূপ উপাদানগুলি
অনুরূপ উপাদানগুলি
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Phospholipase D1 regulates lymphocyte adhesion via upregulation of Rap1 at the plasma membrane.
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Compartmentalized Ras signaling in lymphocytes
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প্রকাশিত: (2009-02-01) -
Costimulators expressed on human endothelial cells modulate antigen-dependent recruitment of circulating T lymphocytes
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প্রকাশিত: (2022-10-01) -
Costimulation: building an immunological synapse.
অনুযায়ী: Dustin, M, অন্যান্য
প্রকাশিত: (1999) -
A quantitative analysis of the contribution of costimulation to T cell activation by the T cell receptor and chimeric antigen receptors
অনুযায়ী: Patel, AB
প্রকাশিত: (2023)