The lymphocyte function-associated antigen-1 receptor costimulates plasma membrane Ras via phospholipase D2.

The lymphocyte function-associated antigen-1 receptor costimulates plasma membrane Ras via phospholipase D2.

Ras activation as a consequence of antigen receptor (T-cell receptor; TCR) engagement on T lymphocytes is required for T-cell development, selection and function. Lymphocyte function-associated antigen-1 (LFA-1) mediates lymphocyte adhesion, stabilization of the immune synapse and bidirectional sign...

书目详细资料
Main Authors:	Mor, A, Campi, G, Du, G, Zheng, Y, Foster, D, Dustin, M, Philips, MR
格式:	Journal article
语言:	English
出版:	2007

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