The lymphocyte function-associated antigen-1 receptor costimulates plasma membrane Ras via phospholipase D2.

Ras activation as a consequence of antigen receptor (T-cell receptor; TCR) engagement on T lymphocytes is required for T-cell development, selection and function. Lymphocyte function-associated antigen-1 (LFA-1) mediates lymphocyte adhesion, stabilization of the immune synapse and bidirectional sign...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors: Mor, A, Campi, G, Du, G, Zheng, Y, Foster, D, Dustin, M, Philips, MR
Format: Journal article
Sprog:English
Udgivet: 2007