Lethal malaria: Marchiafava and Bignami were right.
One hundred and twenty years ago, the Italian malariologists Marchiafava and Bignami proposed that the fundamental pathological process underlying lethal falciparum malaria was microvascular obstruction. Since then, several alternative hypotheses have been proposed. These formed the basis for adjunc...
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
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2013
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_version_ | 1797094247573225472 |
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author | White, N Turner, G Day, N Dondorp, A |
author_facet | White, N Turner, G Day, N Dondorp, A |
author_sort | White, N |
collection | OXFORD |
description | One hundred and twenty years ago, the Italian malariologists Marchiafava and Bignami proposed that the fundamental pathological process underlying lethal falciparum malaria was microvascular obstruction. Since then, several alternative hypotheses have been proposed. These formed the basis for adjunctive interventions, which have either been ineffective or harmful. Recent evidence strongly suggests that Marchiafava and Bignami were right. |
first_indexed | 2024-03-07T04:11:25Z |
format | Journal article |
id | oxford-uuid:c7f29f21-377e-445e-b872-c63d882825a7 |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-07T04:11:25Z |
publishDate | 2013 |
record_format | dspace |
spelling | oxford-uuid:c7f29f21-377e-445e-b872-c63d882825a72022-03-27T06:48:52ZLethal malaria: Marchiafava and Bignami were right.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:c7f29f21-377e-445e-b872-c63d882825a7EnglishSymplectic Elements at Oxford2013White, NTurner, GDay, NDondorp, AOne hundred and twenty years ago, the Italian malariologists Marchiafava and Bignami proposed that the fundamental pathological process underlying lethal falciparum malaria was microvascular obstruction. Since then, several alternative hypotheses have been proposed. These formed the basis for adjunctive interventions, which have either been ineffective or harmful. Recent evidence strongly suggests that Marchiafava and Bignami were right. |
spellingShingle | White, N Turner, G Day, N Dondorp, A Lethal malaria: Marchiafava and Bignami were right. |
title | Lethal malaria: Marchiafava and Bignami were right. |
title_full | Lethal malaria: Marchiafava and Bignami were right. |
title_fullStr | Lethal malaria: Marchiafava and Bignami were right. |
title_full_unstemmed | Lethal malaria: Marchiafava and Bignami were right. |
title_short | Lethal malaria: Marchiafava and Bignami were right. |
title_sort | lethal malaria marchiafava and bignami were right |
work_keys_str_mv | AT whiten lethalmalariamarchiafavaandbignamiwereright AT turnerg lethalmalariamarchiafavaandbignamiwereright AT dayn lethalmalariamarchiafavaandbignamiwereright AT dondorpa lethalmalariamarchiafavaandbignamiwereright |