Predicting cross-reactivity and antigen specificity of T cell receptors

Adaptive immune recognition is mediated by specific interactions between heterodimeric T cell receptors (TCRs) and their cognate peptide-MHC (pMHC) ligands, and the methods to accurately predict TCR:pMHC interaction would have profound clinical, therapeutic and pharmaceutical applications. Herein, w...

Полное описание

Библиографические подробности
Главные авторы: Lee, CH, Salio, M, Napolitani, G, Ogg, G, Simmons, A, Koohy, H
Формат: Journal article
Язык:English
Опубликовано: Frontiers Media 2020