Effective induction of high-titer antibodies by viral vector vaccines.

Protein-in-adjuvant vaccines have shown limited success against difficult diseases such as blood-stage malaria. Here we show that a recombinant adenovirus-poxvirus prime-boost immunization regime (known to induce strong T cell immunogenicity) can also induce very strong antigen-specific antibody res...

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Main Authors: Draper, S, Moore, A, Goodman, A, Long, C, Holder, A, Gilbert, S, Hill, F, Hill, A
格式: Journal article
语言:English
出版: 2008