CAMPATH-IH in multiple sclerosis.

CAMPATH-IH in multiple sclerosis.

In a pilot study, seven patients with multiple sclerosis were treated with CAMPATH-IH which targets the CD52 antigen present on lymphocytes and monocytes. There was a substantial reduction in disease activity as measured by gadoliunium-enhancing lesions on MRI. Encouraged by this result a further se...

Podrobná bibliografie
Hlavní autoři:	Moreau, T, Coles, A, Wing, M, Thorpe, J, Miller, D, Moseley, I, Issacs, J, Hale, G, Clayton, D, Scolding, N, Waldmann, H, Compston, A
Médium:	Journal article
Jazyk:	English
Vydáno:	1996

Podobné jednotky

Preliminary evidence from magnetic resonance imaging for reduction in disease activity after lymphocyte depletion in multiple sclerosis.
Autor: Moreau, T, a další
Vydáno: (1994)

Inflammation, demyelination, and axonal degeneration: Three aspects of the pathogenesis of multiple sclerosis revealed by campath-1H treatment
Autor: Coles, A, a další
Vydáno: (2003)

Campath IH allows low-dose cyclosporine monotherapy in 31 cadaveric renal allograft recipients.
Autor: Calne, R, a další
Vydáno: (1999)

Transient increase in symptoms associated with cytokine release in patients with multiple sclerosis.
Autor: Moreau, T, a další
Vydáno: (1996)

CAMPATH: from concept to clinic.
Autor: Waldmann, H, a další
Vydáno: (2005)

Mechanism of first-dose cytokine-release syndrome by CAMPATH 1-H: involvement of CD16 (FcgammaRIII) and CD11a/CD18 (LFA-1) on NK cells.
Autor: Wing, MG, a další
Vydáno: (1996)

Specificity of monoclonal antibody Campath-1.
Autor: Hale, G, a další
Vydáno: (1988)

Monoclonal antibody treatment exposes three mechanisms underlying the clinical course of multiple sclerosis.
Autor: Coles, A, a další
Vydáno: (1999)

CAMPATH-1H in inflammatory arthritis.
Autor: Watts, R, a další
Vydáno: (1993)

Availability of Campath-1 antibodies for bone marrow transplantation.
Autor: Hale, G, a další
Vydáno: (1995)

CAMPATH-1 monoclonal antibodies in bone marrow transplantation.
Autor: Hale, G, a další
Vydáno: (1994)

Lymphocyte homeostasis following therapeutic lymphocyte depletion in multiple sclerosis.
Autor: Cox, A, a další
Vydáno: (2005)

The CAMPATH-1 antigen (CDw52).
Autor: Hale, G, a další
Vydáno: (1990)

T cell depletion with CAMPATH-1 in allogeneic bone marrow transplantation.
Autor: Hale, G, a další
Vydáno: (1988)

Impact on T-cell depletion and CD34+ cell recovery using humanised CD52 monoclonal antibody (CAMPATH-1H) in BM and PSBC collections; comparison with CAMPATH-1M and CAMPATH-1G.
Autor: Williams, R, a další
Vydáno: (2000)

Recent results using CAMPATH-1 antibodies to control GVHD and graft rejection.
Autor: Hale, G, a další
Vydáno: (1996)

CAMPATH-1 antibodies in stem-cell transplantation.
Autor: Hale, G, a další
Vydáno: (2001)

The window of therapeutic opportunity in multiple sclerosis: evidence from monoclonal antibody therapy.
Autor: Coles, A, a další
Vydáno: (2006)

Campath-1H therapy in refractory ocular inflammatory disease.
Autor: Dick, A, a další
Vydáno: (2000)

Pulsed monoclonal antibody treatment and autoimmune thyroid disease in multiple sclerosis.
Autor: Coles, A, a další
Vydáno: (1999)

Leukaemic relapse after Campath 1-treated bone-marrow transplantation for leukaemia.
Autor: Waldmann, H, a další
Vydáno: (1987)

TREATMENT OF RHEUMATOID-ARTHRITIS WITH HUMANIZED ANTILYMPHOCYTE ANTIBODY CAMPATH-1H
Autor: Watts, R, a další
Vydáno: (1992)

Rat monoclonal antibodies for bone marrow transplantation--the CAMPATH series.
Autor: Waldmann, H, a další
Vydáno: (1985)

Alemtuzumab (Campath-1H) for treatment of lymphoid malignancies in the age of nonmyeloablative conditioning?
Autor: Hale, G, a další
Vydáno: (2002)

Monoclonal antibody therapy of diffuse cutaneous scleroderma with CAMPATH-1H.
Autor: Isaacs, J, a další
Vydáno: (1996)

CAMPATH-1 MOAB IN THE TREATMENT OF REFRACTORY AUTOIMMUNE THROMBOCYTOPENIC PURPURA (ATP)
Autor: Lim, S, a další
Vydáno: (1993)

Campath-1 Abs 'in the bag' for hematological malignancies: the Cape Town experience.
Autor: Novitzky, N, a další
Vydáno: (2004)

Sustained remission of severe resistant autoimmune neutropenia with Campath-1H.
Autor: Killick, S, a další
Vydáno: (1997)

CAMPATH-1 FOLLOWING RENAL-TRANSPLANTATION - A RANDOMIZED TRIAL
Autor: Friend, P, a další
Vydáno: (1988)

In vivo 'purging' of residual disease in CLL with Campath-1H.
Autor: Dyer, M, a další
Vydáno: (1997)

Efficient complement-mediated lysis of cells containing the CAMPATH-1 (CDw52) antigen.
Autor: Xia, M, a další
Vydáno: (1993)

EFFECTS OF MONOCLONAL-ANTIBODIES OF THE CAMPATH SERIES INVIVO - REQUIREMENTS FOR EFFECTIVE ANTIBODY THERAPY
Autor: Dyer, M, a další
Vydáno: (1988)

CAMPATH-1 monoclonal antibody therapy in severe refractory autoimmune thrombocytopenic purpura.
Autor: Lim, S, a další
Vydáno: (1993)

ISOTYPE VARIANTS OF CAMPATH-1 ANTIBODY - REQUIREMENTS FOR EFFECTIVE ANTIBODY ACTION INVIVO
Autor: Dyer, M, a další
Vydáno: (1989)

The effect of treatment with Campath-1H in patients with autoimmune cytopenias.
Autor: Willis, F, a další
Vydáno: (2001)

Engineering multiple-domain forms of the therapeutic antibody CAMPATH-1H: effects on complement lysis.
Autor: Greenwood, J, a další
Vydáno: (1994)

COMPLEMENT LYSIS MEDIATED BY ENGINEERED MULTIPLE-DOMAIN FORMS OF THE THERAPEUTIC ANTIBODY CAMPATH-1H
Autor: Greenwood, J, a další
Vydáno: (1994)

RAT MONOCLONAL-ANTIBODIES FOR BONE-MARROW TRANSPLANTATION (BMT) - THE CAMPATH SERIES
Autor: Waldmann, H, a další
Vydáno: (1985)

A personal history of the CAMPATH-1H antibody.
Autor: Waldmann, H
Vydáno: (2002)

Monoclonal antibody therapy of chronic intraocular inflammation using Campath-1H.
Autor: Isaacs, J, a další
Vydáno: (1995)