Dynamic control of chromatin-associated m6A methylation regulates nascent RNA synthesis
N6-methyladenosine (m6A) methylation is co-transcriptionally deposited on mRNA, but a possible role of m6A on transcription remains poorly understood. Here, we demonstrate that the METTL3/METTL14/WTAP m6A methyltransferase complex (MTC) is localized to many promoters and enhancers and deposits the m...
Prif Awduron: | Xu, W, He, C, Kaye, EG, Li, J, Mu, M, Nelson, GM, Dong, L, Wang, J, Wu, F, Shi, YG, Adelman, K, Lan, F, Shi, Y, Shen, H |
---|---|
Fformat: | Journal article |
Iaith: | English |
Cyhoeddwyd: |
Cell Press
2022
|
Eitemau Tebyg
-
Nascent RNA antagonizes the interaction of a set of regulatory proteins with chromatin
gan: Skalska, L, et al.
Cyhoeddwyd: (2021) -
RNA-RNA Interactions Enable Specific Targeting of Noncoding RNAs to Nascent Pre-mRNAs and Chromatin Sites
gan: Sirokman, Klara, et al.
Cyhoeddwyd: (2017) -
Nascent mRNA damage: depot and disposal
gan: Mark Helm, et al.
Cyhoeddwyd: (2024-08-01) -
Structure of Nascent Chromatin Is Essential for Hematopoietic Lineage Specification
gan: Svetlana Petruk, et al.
Cyhoeddwyd: (2017-04-01) -
Quantifying RNA synthesis at rate-limiting steps of transcription using nascent RNA-sequencing data
gan: Adelina Rabenius, et al.
Cyhoeddwyd: (2022-03-01)