5-methyl-tetrahydrofolate increases nitric oxide bioavailability and decreases superoxide production by improving eNOS coupling and preventing the intracellular oxidation of tetrahy-drobiopterin, in human vessels in vivo

Bibliographic Details
Main Authors:	Antoniades, C, Shirodaria, C, Leeson, P, Lee, J, Warrick, N, Taggart, D, Ratnatunga, C, Pillai, R, Channon, K
Format:	Conference item
Published:	2006

5-methyl-tetrahydrofolic acid increases nitric oxide bioavailability and decreases superoxide production by improving eNOS coupling in human vessels in vivo: Effects on intracellular tetrahydrobiopterin oxidation
by: Antoniades, C, et al.
Published: (2006)

5-Methyl-tetrahydrofolate acid improves endothelial function and decreases superoxide production by improving eNOS coupling and increasing tetrahydrobiopterin bioavailability in human vessels in vivo
by: Antoniades, C, et al.
Published: (2006)

Genetic Polymorphism On Methyl-Tetrahydrofolate-Reductase Affects Vascular Superoxide Generation and Nitric Oxide Bioavailability By Regulating eNOS Coupling in Human Arteries and Veins
by: Antoniades, C, et al.
Published: (2009)

Intravenous infusion of 5-methyl-tetrahydrofolate rapidly improves eNOS Coupling. In human vessels by increasing tetrahydrobiopterin bioavailability
by: Antoniades, C, et al.
Published: (2006)

5-methyl-tetrahydrofolate increases eNOS activity by preventing peroxynitrite-induced oxidation of tetrahydrobiopterin in human vessels
by: Antoniades, C, et al.
Published: (2006)

5-Methyl-tetrahydrofolic acid rapidly improves endothelial function and superoxide production in human atherosclerosis: Effects on tetrahyd robiopterin-dependent eNOS coupling
by: Antoniades, C, et al.
Published: (2006)

Plasma asymmetrical-dimethyl-arginine affects eNOS vascular superoxide radical production and nitric oxide bioavailability in human arteries and veins
by: Antoniades, C, et al.
Published: (2008)

Chronic treatment with folic acid improves nitric oxide bioavailability and decreases superoxide production in human vessels, through tetrahydrobiopterin-mediated improvement of eNOS coupling
by: Antoniades, C, et al.
Published: (2007)

Genetic Variability of Methyl-Tetrahydrofolate-Reductase Modifies eNOS Coupling in Human Arteries and Veins: Effects on Vascular Superoxide Generation and Nitric Oxide Bioavailabllity
by: Antoniades, C, et al.
Published: (2008)

The common genetic polymorphism C677T of methyltetrahydrofolate reductase regulates nitric oxide bioavailability and vascular superoxide production via modulation of eNOS coupling in human vessels
by: Antoniades, C, et al.
Published: (2007)

Polymorphism of MTHFR gene affects vascular redox and nitric oxide bioavailability by modifying eNOS coupling
by: Antoniades, C, et al.
Published: (2008)

Direct effects of 5-methyl-tetrahydrofolate on vascular endotheliurn and superoxide production in human arteries and veins
by: Antoniades, C, et al.
Published: (2006)

Genetic variability of MTHFR affects vascular redox and nitric oxide bioavailability in human vessels, by modifying eNOS coupling
by: Antoniades, C, et al.
Published: (2008)

Effects of 5-methyl-tetrahydrofolic acid on endothelial function and vascular superoxide production in human coronary artery disease
by: Antoniades, C, et al.
Published: (2006)

5-methyl-tetrahydrofolate acid improves endothelial function and decreases superoxide production in vessels from patients with coronary artery disease
by: Antoniades, C, et al.
Published: (2006)

Rapid effects of 5-methyl-tetrahydrofolic acid on endothelial function and vascular superoxide production in human coronary artery disease
by: Antoniades, C, et al.
Published: (2006)

Low- and high- dose treatment with folic acid, equally improve endothelial function and decrease superoxide production in human vessels via tetrahydrobiopterin-mediated eNOS coupling
by: Antoniades, C, et al.
Published: (2007)

Plasma asymmetrical-dimethyl-arginine (ADMA) regulates nitric oxide bioavailability and vascular superoxide production in human vessels
by: Antoniades, C, et al.
Published: (2007)

Soluble CD40-ligand levels are associated with vascular superoxide production and eNOS coupling in human vessels: Interrelationships with homocysteine biosynthetic pathway
by: Antoniades, C, et al.
Published: (2008)

5-methyltetrahydrofolate rapidly improves endothelial function and decreases superoxide production in human vessels: effects on vascular tetrahydrobiopterin availability and endothelial nitric oxide synthase coupling.
by: Antoniades, C, et al.
Published: (2006)

Association of plasma asymmetrical dimethylarginine (ADMA) with elevated vascular superoxide production and endothelial nitric oxide synthase uncoupling: implications for endothelial function in human atherosclerosis.
by: Antoniades, C, et al.
Published: (2009)

Plasma asymmetrical-dimethyl-arginine (ADMA) as a regulator of vascular redox and nitric oxide bioavailability in human vessels
by: Antoniades, C, et al.
Published: (2007)

Oral Atorvastatin Treatment Improves NO Bioavailability and Vascular Redox State in the Human Arterial Wall, via a Tetrahydrobiopterin-Mediated Improvement of eNOS Coupling
by: Antoniades, C, et al.
Published: (2011)

Stoichiometric relationships between endothelial tetrahydrobiopterin, endothelial NO synthase (eNOS) activity, and eNOS coupling in vivo: insights from transgenic mice with endothelial-targeted GTP cyclohydrolase 1 and eNOS overexpression.
by: Bendall, J, et al.
Published: (2005)

RAPID, DIRECT EFFECTS OF STATIN TREATMENT ON ARTERIAL REDOX STATE AND NITRIC OXIDE BIOAVAILABILITY IN HUMAN ATHEROSCLEROSIS VIA TETRAHYDROBIOPTERIN-MEDIATED ENOS COUPLING
by: Antoniades, C, et al.
Published: (2011)

Quantitative regulation of intracellular endothelial nitric-oxide synthase (eNOS) coupling by both tetrahydrobiopterin-eNOS stoichiometry and biopterin redox status: insights from cells with tet-regulated GTP cyclohydrolase I expression.
by: Crabtree, M, et al.
Published: (2009)

Regulation of endothelial nitric oxide synthase (eNOS) by tetrahydrobiopterin in vascular disease
by: Alp, N, et al.
Published: (2004)

Pre-operative flow mediated dilatation in patients undergoing coronary artery bypass surgery: Prediction of NO-bioavailability and vascular superoxide production in arterial and vein grafts
by: Antoniades, C, et al.
Published: (2008)

Plasma levels of sCD40-ligand interact with homocysteine biosynthetic pathway and predict eNOS coupling in human vessels: effects on vascular redox state
by: Antoniades, C, et al.
Published: (2008)

Preoperative evaluation of flow-mediated dilatation in the left radial artery or the right brachial artery, as a predictor of nitric-oxide bioavailability in coronary artery bypass grafts
by: Antoniades, C, et al.
Published: (2006)

Expression and functional analysis of endothelial nitric oxide synthase (eNOS) in human placenta.
by: Rossmanith, W, et al.
Published: (1999)

Relationships between nitric oxide-mediated endothelial function, eNOS coupling and blood pressure revealed by eNOS-GTP cyclohydrolase 1 double transgenic mice.
by: Adlam, D, et al.
Published: (2007)

A pivotal role for tryptophan 447 in enzymatic coupling of human endothelial nitric oxide synthase (eNOS): effects on tetrahydrobiopterin-dependent catalysis and eNOS dimerization.
by: Benson, M, et al.
Published: (2013)

Relation of preoperative radial artery flow-mediated dilatation to nitric oxide bioavailability in radial artery grafts used in off-pump coronary artery bypass grafting.
by: Antoniades, C, et al.
Published: (2009)

Cavin-2 regulates the activity and stability of endothelial nitric-oxide synthase (eNOS) in angiogenesis
by: Boopathy, Gandhi T. K., et al.
Published: (2018)

Endothelial nitric oxide synthase dysfunction in diabetic mice: importance of tetrahydrobiopterin in eNOS dimerisation.
by: Cai, S, et al.
Published: (2005)

Chronic treatment with folic acid improves endothelial function and decreases superoxide production in human vessels. A double blind placebo control study
by: Shirodaria, C, et al.
Published: (2005)

Tetrahydrobiopterin availability directly regulates eNOS coupling in tet-regulatable cells
by: Crabtree, M, et al.
Published: (2007)

Superoxide generation by NAD(P)H oxidase in human sphenous vein: Interaction with nitric oxide
by: Guzik, T, et al.
Published: (2000)

Direct improvement of endothelial function and superoxide production in human vessels, by oral folic acid treatment: A double blind placebo controlled study
by: Antoniades, C, et al.
Published: (2005)

5-methyl-tetrahydrofolate increases nitric oxide bioavailability and decreases superoxide production by improving eNOS coupling and preventing the intracellular oxidation of tetrahy-drobiopterin, in human vessels in vivo

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