The synthesis of oligomers of oxetane-based dipeptide isosteres derived from L-rhamnose or D-xylose.

Routes to oligomers (dimers, tetramers, hexamers) of five oxetane-based dipeptide isosteres have been established. Methyl 2,4-anhydro-5-azido-5-deoxy-L-rhamnonate 'monomer' led, by coupling the corresponding carboxylic acid and amine, to a 'dimer'. Reverse-aldol ring-opening occu...

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Hlavní autoři: Johnson, S, Jenkinson, S, Angus, D, Pérez-Victoria, I, Claridge, T, Fleet, G, Jones, J
Médium: Journal article
Jazyk:English
Vydáno: 2005