Dissecting heterogeneity in GWAS meta-analysis

Dissecting heterogeneity in GWAS meta-analysis

<p>Statistical heterogeneity refers to differences among results of studies combined in a meta-analysis beyond that expected by chance. On the one hand, excessive heterogeneity can diminish power to discover genetic signals; on the other, moderate heterogeneity can reveal important biological...

Bibliográfalaš dieđut
Váldodahkki:	Magosi, L
Eará dahkkit:	Farrall, M
Materiálatiipa:	Oahppočájánas
Giella:	English
Almmustuhtton:	2017
Fáttát:	cardiovascular genetics meta-analysis statistical genetics heterogeneity prior distributions coronary artery disease genetic association meta-analyses Bayesian methods genetic epidemiology LPA coronary heart disease genome-wide association studies

Geahča maid

Identification of CAD candidate genes in GWAS loci and their expression in vascular cells[S]
Dahkki: Ayca Erbilgin, et al.
Almmustuhtton: (2013-07-01)

Beyond the Basics: Unraveling the Complexity of Coronary Artery Calcification
Dahkki: Satwat Hashmi, et al.
Almmustuhtton: (2023-12-01)

Inflammation-Related Risk Loci in Genome-Wide Association Studies of Coronary Artery Disease
Dahkki: Carina Mauersberger, et al.
Almmustuhtton: (2021-02-01)

Genetics of spontaneous cervical and coronary artery dissections
Dahkki: Isabel Rada, et al.
Almmustuhtton: (2023-05-01)

Analysis of two single-nucleotide polymorphisms (rs2241766 and rs1501299) of the adiponectin gene in patients with coronary artery disease and coronary slow flow
Dahkki: Muhammad Diah, et al.
Almmustuhtton: (2020-08-01)

Statistical power in COVID-19 case-control host genomic study design
Dahkki: Yu-Chung Lin, et al.
Almmustuhtton: (2020-12-01)

Cumulative evidence for association between genetic polymorphisms and esophageal cancer susceptibility: A review with evidence from meta‐analysis and genome‐wide association studies
Dahkki: Jie Tian, et al.
Almmustuhtton: (2019-03-01)

Genetic Variation at the ADAMTS7 Locus is Associated With Reduced Severity of Coronary Artery Disease
Dahkki: Kenneth Chan, et al.
Almmustuhtton: (2017-11-01)

ForestPMPlot: A Flexible Tool for Visualizing Heterogeneity Between Studies in Meta-analysis
Dahkki: Eun Yong Kang, et al.
Almmustuhtton: (2016-07-01)

Local Ancestry and Clinical Cardiovascular Events Among African Americans From the Atherosclerosis Risk in Communities Study
Dahkki: Aditi Shendre, et al.
Almmustuhtton: (2017-04-01)

Scientific Contributions of Population-Based Studies to Cardiovascular Epidemiology in the GWAS Era
Dahkki: Wolfgang Lieb, et al.
Almmustuhtton: (2018-06-01)

Pathogenesis of premature coronary artery disease: Focus on risk factors and genetic variants
Dahkki: Haiming Wang, et al.
Almmustuhtton: (2022-03-01)

Mendelian Randomization and GWAS Meta Analysis Revealed the Risk-Increasing Effect of Schizophrenia on Cancers
Dahkki: Kai Yuan, et al.
Almmustuhtton: (2022-09-01)

Novel hypotheses emerging from GWAS in migraine?
Dahkki: Arn M. J. M. van den Maagdenberg, et al.
Almmustuhtton: (2019-01-01)

Learning the optimal scale for GWAS through hierarchical SNP aggregation
Dahkki: Florent Guinot, et al.
Almmustuhtton: (2018-11-01)

Metabolic Mediators of the Effects of Family History and Genetic Risk Score on Coronary Heart Disease—Findings From the Malmö Diet and Cancer Study
Dahkki: Josef Fritz, et al.
Almmustuhtton: (2017-03-01)

Maintenance of Complex Trait Variation: Classic Theory and Modern Data
Dahkki: Evan M. Koch, et al.
Almmustuhtton: (2021-11-01)

Multiple susceptibility loci at chromosome 11q23.3 are associated with plasma triglyceride in East Asians[S]
Dahkki: Bayasgalan Gombojav, et al.
Almmustuhtton: (2016-02-01)

Association Study of Lipoprotein (a) Genetic Markers, Traditional Risk Factors and Coronary Heart Disease in HIV-1-infected Patients
Dahkki: Lander eEgaña-Gorroño, et al.
Almmustuhtton: (2012-12-01)

Genetic Factors for Coronary Heart Disease and Their Mechanisms: A Meta-Analysis and Comprehensive Review of Common Variants from Genome-Wide Association Studies
Dahkki: Khairul Anwar Zarkasi, et al.
Almmustuhtton: (2022-10-01)

Genomic analyses of claw disorders in Holstein cows: Genetic parameters, trait associations, and genome-wide associations considering interactions of SNP and heat stress
Dahkki: Niklas Sölzer, et al.
Almmustuhtton: (2022-10-01)

Genome-wide association study of subclinical interstitial lung disease in MESA
Dahkki: Ani Manichaikul, et al.
Almmustuhtton: (2017-05-01)

Identification of the shared genetic architecture underlying seven autoimmune diseases with GWAS summary statistics
Dahkki: Yuping Wang, et al.
Almmustuhtton: (2024-01-01)

Relationship Between Time‐Varying Achieved High‐Density Lipoprotein Cholesterol and Risk of Coronary Events Depends on Haptoglobin Phenotype Within the ACCORD Lipid Study
Dahkki: Rachel A. Warren, et al.
Almmustuhtton: (2023-10-01)

Combining geographic region with meta-analysis to map the potential association between three genetic polymorphisms and coronary artery disease
Dahkki: Hua Lin, et al.
Almmustuhtton: (2013-01-01)

The association between Matrix Metallo-proteinases-9 (MMP-9) gene family polymorphisms and risk of Coronary Artery Disease (CAD): a systematic review and meta-analysis
Dahkki: Reza Hassanzadeh-Makoui, et al.
Almmustuhtton: (2020-05-01)

The Effect of Population Structure on Murine Genome-Wide Association Studies
Dahkki: Meiyue Wang, et al.
Almmustuhtton: (2021-09-01)

Multivariate GWAS of psychiatric disorders and their cardinal symptoms reveal two dimensions of cross-cutting genetic liabilities
Dahkki: Travis T. Mallard, et al.
Almmustuhtton: (2022-06-01)

Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes
Dahkki: Jasmin Divers, et al.
Almmustuhtton: (2017-12-01)

An analysis of genetically regulated gene expression across multiple tissues implicates novel gene candidates in Alzheimer’s disease
Dahkki: Zachary F. Gerring, et al.
Almmustuhtton: (2020-04-01)

Meta-analysis for genome-wide association studies using case-control design: application and practice
Dahkki: Sungryul Shim, et al.
Almmustuhtton: (2016-12-01)

Genome-wide association study of plasma lipoprotein(a) levels identifies multiple genes on chromosome 6q[S]
Dahkki: Carole Ober, et al.
Almmustuhtton: (2009-05-01)

Haptoglobin phenotype and intensive glycemic control for coronary artery disease risk reduction in people with type two diabetes: The Veterans Affairs Diabetes Trial
Dahkki: Leah E Cahill, et al.
Almmustuhtton: (2024-06-01)

Effects of ADIPOQ polymorphisms on individual susceptibility to coronary artery disease: a meta-analysis
Dahkki: Zhiyuan Wang, et al.
Almmustuhtton: (2019-01-01)

Interaction of gene polymorphisms in the risk of coronary artery disease and random amplified polymorphic DNA analysis of coronary artery disease
Dahkki: Chu, Wern Cui
Almmustuhtton: (2015)

Putting Into Perspective the Hazards of Untreated Familial Hypercholesterolemia
Dahkki: Paul N. Hopkins
Almmustuhtton: (2017-11-01)

Similar Genetic Architecture of Alzheimer’s Disease and Differential APOE Effect Between Sexes
Dahkki: Hao Wang, et al.
Almmustuhtton: (2021-05-01)

Into the Wild: GWAS Exploration of Non-coding RNAs
Dahkki: Hector Giral, et al.
Almmustuhtton: (2018-12-01)

Genome-Wide Association Studies (GWAS) Approaches for the Detection of Genetic Variants Associated with Antibiotic Resistance: A Systematic Review
Dahkki: Jeanneth Mosquera-Rendón, et al.
Almmustuhtton: (2023-11-01)

Dissecting the shared genetic architecture between endometriosis and polycystic ovary syndrome
Dahkki: Hangjing Tan, et al.
Almmustuhtton: (2024-04-01)