BMP pathway antagonism by Grem1 regulates epithelial cell fate in intestinal regeneration

<p><strong>Background and aims:</strong> In homeostasis, intestinal cell fate is controlled by balanced gradients of morphogen signalling. The Bone Morphogenetic Protein (BMP) pathway has a physiological, pro-differentiation role, predominantly inferred through previous experimenta...

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Main Authors: Koppens, MAJ, Davis, H, Valbuena, GN, Mulholland, E, Simmons, A, Nasreddin, N, East, J, Friedrich, M, Antanaviciute, A, Leedham, S
格式: Journal article
语言:English
出版: Elsevier 2021