Opening of the outer membrane protein channel in tripartite efflux pumps is induced by interaction with the membrane fusion partner.

Opening of the outer membrane protein channel in tripartite efflux pumps is induced by interaction with the membrane fusion partner.

The multiple transferable resistance (MTR) pump, from Neisseria gonorrhoeae, is typical of the specialized machinery used to translocate drugs across the inner and outer membranes of Gram-negative bacteria. It consists of a tripartite complex composed of an inner-membrane transporter, MtrD, a peripl...

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Bibliographic Details
Main Authors: Janganan, T, Zhang, L, Bavro, V, Matak-Vinkovic, D, Barrera, N, Burton, M, Steel, P, Robinson, C, Borges-Walmsley, M, Walmsley, A
Format: Journal article
Language:English
Published: 2011

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