Translating the immunogenicity of prime-boost immunization with ChAd63 and MVA ME-TRAP from malaria naive to malaria-endemic populations.

Translating the immunogenicity of prime-boost immunization with ChAd63 and MVA ME-TRAP from malaria naive to malaria-endemic populations.

To induce a deployable level of efficacy, a successful malaria vaccine would likely benefit from both potent cellular and humoral immunity. These requirements are met by a heterologous prime-boost immunization strategy employing a chimpanzee adenovirus vector followed by modified vaccinia Ankara (MV...

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Detalles Bibliográficos
Autores principales: Kimani, D, Jagne, Y, Cox, M, Kimani, E, Bliss, C, Gitau, E, Ogwang, C, Afolabi, M, Bowyer, G, Collins, K, Edwards, N, Hodgson, S, Duncan, C, Spencer, A, Knight, MG, Drammeh, A, Anagnostou, N, Berrie, E, Moyle, S, Gilbert, S, Soipei, P, Okebe, J, Colloca, S, Cortese, R, Viebig, N
Formato: Journal article
Lenguaje:English
Publicado: 2014

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