Translating the immunogenicity of prime-boost immunization with ChAd63 and MVA ME-TRAP from malaria naive to malaria-endemic populations.
To induce a deployable level of efficacy, a successful malaria vaccine would likely benefit from both potent cellular and humoral immunity. These requirements are met by a heterologous prime-boost immunization strategy employing a chimpanzee adenovirus vector followed by modified vaccinia Ankara (MV...
Glavni autori: | Kimani, D, Jagne, Y, Cox, M, Kimani, E, Bliss, C, Gitau, E, Ogwang, C, Afolabi, M, Bowyer, G, Collins, K, Edwards, N, Hodgson, S, Duncan, C, Spencer, A, Knight, MG, Drammeh, A, Anagnostou, N, Berrie, E, Moyle, S, Gilbert, S, Soipei, P, Okebe, J, Colloca, S, Cortese, R, Viebig, N |
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Format: | Journal article |
Jezik: | English |
Izdano: |
2014
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Slični predmeti
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Safety and immunogenicity of heterologous prime-boost immunisation with Plasmodium falciparum malaria candidate vaccines, ChAd63 ME-TRAP and MVA ME-TRAP, in healthy Gambian and Kenyan adults.
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Safety and immunogenicity of heterologous prime-boost immunisation with Plasmodium falciparum malaria candidate vaccines, ChAd63 ME-TRAP and MVA ME-TRAP, in healthy Gambian and Kenyan adults.
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