Cytokine gene therapy in experimental allergic encephalomyelitis by injection of plasmid DNA-cationic liposome complex into the central nervous system.
Experimental allergic encephalomyelitis (EAE) is an autoimmune disease of the central nervous system with many similarities to multiple sclerosis. The main effector cells involved are CD4+ T cells, recognizing encephalitogenic epitopes within the central nervous system, and macrophages, both of whic...
Huvudupphovsmän: | Croxford, J, Triantaphyllopoulos, K, Podhajcer, O, Feldmann, M, Baker, D, Chernajovsky, Y |
---|---|
Materialtyp: | Journal article |
Språk: | English |
Publicerad: |
1998
|
Liknande verk
-
Different therapeutic outcomes in experimental allergic encephalomyelitis dependent upon the mode of delivery of IL-10: a comparison of the effects of protein, adenoviral or retroviral IL-10 delivery into the central nervous system.
av: Croxford, J, et al.
Publicerad: (2001) -
Gene therapy for chronic relapsing experimental allergic encephalomyelitis using cells expressing a novel soluble p75 dimeric TNF receptor.
av: Croxford, J, et al.
Publicerad: (2000) -
Local gene therapy with CTLA4-immunoglobulin fusion protein in experimental allergic encephalomyelitis.
av: Croxford, J, et al.
Publicerad: (1998) -
Control of established experimental allergic encephalomyelitis by inhibition of tumor necrosis factor (TNF) activity within the central nervous system using monoclonal antibodies and TNF receptor-immunoglobulin fusion proteins.
av: Baker, D, et al.
Publicerad: (1994) -
Biological efficacy and toxicity of naked plasmid DNA and cationic liposome-DNA complexes in ovine lung
av: Renwick, L, et al.
Publicerad: (2003)