Structure and kinetic characterization of human sperm-specific glyceraldehyde-3-phosphate dehydrogenase, GAPDS.

Structure and kinetic characterization of human sperm-specific glyceraldehyde-3-phosphate dehydrogenase, GAPDS.

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hGAPDS (human sperm-specific glyceraldehyde-3-phosphate dehydrogenase) is a glycolytic enzyme essential for the survival of spermatozoa, and constitutes a potential target for non-hormonal contraception. However, enzyme characterization of GAPDS has been hampered by the difficulty in producing solub...

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Bibliographic Details
Main Authors:	Chaikuad, A, Shafqat, N, Al-Mokhtar, R, Cameron, G, Clarke, A, Brady, R, Oppermann, U, Frayne, J, Yue, W
Format:	Journal article
Language:	English
Published:	2011

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