Derisking the Cu-mediated (18)F-fluorination of heterocyclic positron emission tomography radioligands

Molecules labeled with fluorine-18 ((18)F) are used in positron emission tomography to visualize, characterize and measure biological processes in the body. Despite recent advances in the incorporation of (18)F onto arenes, the development of general and efficient approaches to label radioligands ne...

Full description

Bibliographic Details
Main Authors: Taylor, N, Emer, E, Preshlock, S, Schedler, M, Tredwell, M, Verhoog, S, Mercier, J, Genicot, C, Gouverneur, V
Format: Journal article
Language:English
Published: American Chemical Society 2017