Evolutionarily conserved antigens in autoimmune disease: implications for an infective aetiology.

The immune system has evolved to eliminate or inactivate infectious organisms. An inappropriate response against self-components (autoantigens) can result in autoimmune disease. Here we examine the hypothesis that some evolutionarily conserved proteins, present in pathogenic and commensal organisms...

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Bibliographic Details
Main Authors: Wegner, N, Wait, R, Venables, P
Format: Journal article
Language:English
Published: 2009