Mapping the binding site of a cross-reactive Plasmodium falciparum PfEMP1 monoclonal antibody inhibitory of ICAM-1 binding

Mapping the binding site of a cross-reactive Plasmodium falciparum PfEMP1 monoclonal antibody inhibitory of ICAM-1 binding

The virulence of Plasmodium falciparum is linked to the ability of infected erythrocytes (IE) to adhere to the vascular endothelium, mediated by P. falciparum erythrocyte membrane protein 1 (PfEMP1). In this article, we report the functional characterization of an mAb that recognizes a panel of PfEM...

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Bibliographic Details
Main Authors:	Lennartz, F, Bengtsson, A, Olsen, R, Joergensen, L, Brown, A, Remy, L, Man, P, Forest, E, Barfod, L, Adams, Y, Higgins, M, Jensen, A
Format:	Journal article
Language:	English
Published:	American Association of Immunologists 2015

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